Mineralocorticoid receptor antagonists: emerging roles in cardiovascular medicine

John W FunderPrince Henry's Institute, Clayton, Victoria, AustraliaAbstract: Spironolactone was first developed over 50 years ago as a potent mineralocorticoid receptor (MR) antagonist with undesirable side effects; it was followed a decade ago by eplerenone, which is less potent but much mo...

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Bibliographic Details
Main Author: Funder JW
Format: Article
Language:English
Published: Dove Medical Press 2013-10-01
Series:Integrated Blood Pressure Control
Online Access:http://www.dovepress.com/mineralocorticoid-receptor-antagonists-emerging-roles-in-cardiovascula-a14583