(−)-Methyl-Oleocanthal, a New Oleocanthal Metabolite Reduces LPS-Induced Inflammatory and Oxidative Response: Molecular Signaling Pathways and Histones Epigenetic Modulation

(−)-Methyl-Oleocanthal, a New Oleocanthal Metabolite Reduces LPS-Induced Inflammatory and Oxidative Response: Molecular Signaling Pathways and Histones Epigenetic Modulation

The antioxidant and anti-inflammatory responses of (−)-methyl-oleocanthal (met-OLE), a new metabolite of the extra virgin olive oil (EVOO) phenolic oleocanthal (OLE), were explored in lipopolysaccharide (LPS)-induced murine peritoneal macrophages. Possible signaling pathways and epigenetic modulatio...

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Bibliographic Details
Main Authors: Tatiana Montoya, Catalina Alarcón-de-la-Lastra, María Luisa Castejón, Juan Ortega-Vidal, Joaquín Altarejos, Marina Sánchez-Hidalgo
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Antioxidants
Subjects:
antioxidant
histones
inflammation
macrophages
metabolite
methylation
Online Access:https://www.mdpi.com/2076-3921/11/1/56

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