Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.

Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.

Systemic lupus erythematosus is a complex and potentially fatal autoimmune disease, characterized by autoantibody production and multi-organ damage. By a genome-wide association study (320 patients and 1,500 controls) and subsequent replication altogether involving a total of 3,300 Asian SLE patient...

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Main Authors: Wanling Yang, Nan Shen, Dong-Qing Ye, Qiji Liu, Yan Zhang, Xiao-Xia Qian, Nattiya Hirankarn, Dingge Ying, Hai-Feng Pan, Chi Chiu Mok, Tak Mao Chan, Raymond Woon Sing Wong, Ka Wing Lee, Mo Yin Mok, Sik Nin Wong, Alexander Moon Ho Leung, Xiang-Pei Li, Yingyos Avihingsanon, Chun-Ming Wong, Tsz Leung Lee, Marco Hok Kung Ho, Pamela Pui Wah Lee, Yuk Kwan Chang, Philip H Li, Ruo-Jie Li, Lu Zhang, Wilfred Hing Sang Wong, Irene Oi Lin Ng, Chak Sing Lau, Pak Chung Sham, Yu Lung Lau, Asian Lupus Genetics Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2820522?pdf=render

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