Mass spectrometry data and size exclusion chromatography profiles of Australian taipan venom toxins
The compositions of paradoxin and taipoxin (PDx and TPx, respectively) were investigated using size exclusion chromatography (SEC) and nano-electrospray ionization mass spectrometry (nano-ESI-MS). The elution profiles from size exclusion chromatography of the venoms from Oxyuranus microlepidotus and...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2016-12-01
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| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340916305777 |
| _version_ | 1819012125496967168 |
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| author | Julian A. Harrison J. Andrew Aquilina |
| author_facet | Julian A. Harrison J. Andrew Aquilina |
| author_sort | Julian A. Harrison |
| collection | DOAJ |
| description | The compositions of paradoxin and taipoxin (PDx and TPx, respectively) were investigated using size exclusion chromatography (SEC) and nano-electrospray ionization mass spectrometry (nano-ESI-MS). The elution profiles from size exclusion chromatography of the venoms from Oxyuranus microlepidotus and Oxyuranus scutellatus were similar. Fractions corresponding to the trimeric toxins were treated with guanidinium hydrochloride and the individual subunits were separated by HPLC. In this report we present the size exclusion chromatography profiles for these toxins, and the nano-ESI mass spectra of the subunits after separation by HPLC: the first such comparative study of these toxins at the protein level. Data in this article are associated with the research article published in Toxicon: “Insight into the subunit arrangement and diversity of paradoxin and taipoxin” (J.A. Harrison, J.A. Aquilina, 2016) [1]. |
| first_indexed | 2024-12-21T01:39:05Z |
| format | Article |
| id | doaj.art-f7ddf43f1580487b8073b69d947835ac |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-21T01:39:05Z |
| publishDate | 2016-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-f7ddf43f1580487b8073b69d947835ac2022-12-21T19:20:13ZengElsevierData in Brief2352-34092016-12-019C50150710.1016/j.dib.2016.09.005Mass spectrometry data and size exclusion chromatography profiles of Australian taipan venom toxinsJulian A. Harrison0J. Andrew Aquilina1School of Biological Sciences, Faculty of Science, Medicine and Health, University of Wollongong, AustraliaSchool of Biological Sciences, Faculty of Science, Medicine and Health, University of Wollongong, AustraliaThe compositions of paradoxin and taipoxin (PDx and TPx, respectively) were investigated using size exclusion chromatography (SEC) and nano-electrospray ionization mass spectrometry (nano-ESI-MS). The elution profiles from size exclusion chromatography of the venoms from Oxyuranus microlepidotus and Oxyuranus scutellatus were similar. Fractions corresponding to the trimeric toxins were treated with guanidinium hydrochloride and the individual subunits were separated by HPLC. In this report we present the size exclusion chromatography profiles for these toxins, and the nano-ESI mass spectra of the subunits after separation by HPLC: the first such comparative study of these toxins at the protein level. Data in this article are associated with the research article published in Toxicon: “Insight into the subunit arrangement and diversity of paradoxin and taipoxin” (J.A. Harrison, J.A. Aquilina, 2016) [1].http://www.sciencedirect.com/science/article/pii/S2352340916305777 |
| spellingShingle | Julian A. Harrison J. Andrew Aquilina Mass spectrometry data and size exclusion chromatography profiles of Australian taipan venom toxins Data in Brief |
| title | Mass spectrometry data and size exclusion chromatography profiles of Australian taipan venom toxins |
| title_full | Mass spectrometry data and size exclusion chromatography profiles of Australian taipan venom toxins |
| title_fullStr | Mass spectrometry data and size exclusion chromatography profiles of Australian taipan venom toxins |
| title_full_unstemmed | Mass spectrometry data and size exclusion chromatography profiles of Australian taipan venom toxins |
| title_short | Mass spectrometry data and size exclusion chromatography profiles of Australian taipan venom toxins |
| title_sort | mass spectrometry data and size exclusion chromatography profiles of australian taipan venom toxins |
| url | http://www.sciencedirect.com/science/article/pii/S2352340916305777 |
| work_keys_str_mv | AT julianaharrison massspectrometrydataandsizeexclusionchromatographyprofilesofaustraliantaipanvenomtoxins AT jandrewaquilina massspectrometrydataandsizeexclusionchromatographyprofilesofaustraliantaipanvenomtoxins |