Reliability and cross-country equivalence of the 8-item version of the Patient Health Questionnaire (PHQ-8) for the assessment of depression: results from 27 countries in EuropeResearch in context

Summary: Background: The 8-item version of the Patient Health Questionnaire (PHQ-8) is one of the self-reported questionnaires most frequently used worldwide for the screening and severity assessment of depression. However, in some European countries its reliability is unknown, and it is unclear wh...

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Main Authors: Jorge Arias de la Torre, Gemma Vilagut, Amy Ronaldson, Jose M. Valderas, Ioannis Bakolis, Alex Dregan, Antonio J. Molina, Fernando Navarro-Mateu, Katherine Pérez, Xavier Bartoll-Roca, Matilde Elices, Víctor Pérez-Sola, Antoni Serrano-Blanco, Vicente Martín, Jordi Alonso
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:The Lancet Regional Health. Europe
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666776223000789
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author Jorge Arias de la Torre
Gemma Vilagut
Amy Ronaldson
Jose M. Valderas
Ioannis Bakolis
Alex Dregan
Antonio J. Molina
Fernando Navarro-Mateu
Katherine Pérez
Xavier Bartoll-Roca
Matilde Elices
Víctor Pérez-Sola
Antoni Serrano-Blanco
Vicente Martín
Jordi Alonso
author_facet Jorge Arias de la Torre
Gemma Vilagut
Amy Ronaldson
Jose M. Valderas
Ioannis Bakolis
Alex Dregan
Antonio J. Molina
Fernando Navarro-Mateu
Katherine Pérez
Xavier Bartoll-Roca
Matilde Elices
Víctor Pérez-Sola
Antoni Serrano-Blanco
Vicente Martín
Jordi Alonso
author_sort Jorge Arias de la Torre
collection DOAJ
description Summary: Background: The 8-item version of the Patient Health Questionnaire (PHQ-8) is one of the self-reported questionnaires most frequently used worldwide for the screening and severity assessment of depression. However, in some European countries its reliability is unknown, and it is unclear whether its psychometric properties vary between European countries. Therefore, the aim of this study was to assess the internal structure, reliability and cross-country equivalence of the PHQ-8 in Europe. Methods: All participants from the 27 countries included in the second wave of the European Health Interview Survey (EHIS-2) between 2014 and 2015 with complete information on the PHQ-8 were included (n = 258,888). The internal structure of the PHQ-8 was assessed using confirmatory factor analyses (CFA) for categorical items. Additionally, the reliability of the questionnaire was assessed based on the internal consistency, Item Response Theory information functions, and item-discrimination (using Graded Response Models), and the cross-country equivalence based on multi-group CFA. Findings: The PHQ-8 shows high internal consistency for all countries. The countries in which the PHQ-8 was more reliable were Romania, Bulgaria and Cyprus and less reliable were Iceland, Norway and Austria. The PHQ-8 item with highest discrimination was item 2 (feeling down, depressed, or hopeless) in 24 of the 27 countries. Measurement invariance between countries in Europe was observed from multigroup CFA at the configural, metric and scalar levels. Interpretation: The results from our study, likely the largest study to the date assessing the internal structure, reliability and cross-country comparability of a self-reported mental health assessment measure, shows that the PHQ-8 has an adequate reliability and cross-country equivalence across the 27 European countries included. These results highlight the suitability of the comparisons of the PHQ-8 scores in Europe. They could be helpful to improve the screening and severity assessment of depressive symptoms at the European level. Funding: This work was partially funded by CIBER Epidemiology and Public Health (CIBERESP) as part of the Intramural call of 2021 (ESP21PI05).
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spelling doaj.art-f7de01a8071547309a5773348f653ef62023-06-08T04:19:57ZengElsevierThe Lancet Regional Health. Europe2666-77622023-08-0131100659Reliability and cross-country equivalence of the 8-item version of the Patient Health Questionnaire (PHQ-8) for the assessment of depression: results from 27 countries in EuropeResearch in contextJorge Arias de la Torre0Gemma Vilagut1Amy Ronaldson2Jose M. Valderas3Ioannis Bakolis4Alex Dregan5Antonio J. Molina6Fernando Navarro-Mateu7Katherine Pérez8Xavier Bartoll-Roca9Matilde Elices10Víctor Pérez-Sola11Antoni Serrano-Blanco12Vicente Martín13Jordi Alonso14Care in Long Term Conditions Research Division, King’s College London, London, UK; CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain; Institute of Biomedicine (IBIOMED), University of Leon, Leon, Spain; Corresponding author. JCMB, Second Floor, Office 2.16. 57 Waterloo Road, London SE1 8WA, UK.CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain; Health Services Research Group, Hospital del Mar Medical Research Institute (IMIM), Barcelona, SpainInstitute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UKDepartment of Medicine, National University of Singapore, Singapore; Department of Family Medicine, National University Health System, Singapore; Centre for Research in Health Systems Performance (CRiHSP), National University Health System, SingaporeInstitute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UKInstitute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UKCIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain; Institute of Biomedicine (IBIOMED), University of Leon, Leon, SpainCIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain; Unidad de Docencia, Investigación y Formación en Salud Mental (UDIF-SM), Servicio Murciano de Salud, Murcia, Spain; IMIB-Arrixaca, Murcia, SpainCIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain; Agència de Salut Pública de Barcelona (ASPB), Barcelona, Spain; Institut d’Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, SpainAgència de Salut Pública de Barcelona (ASPB), Barcelona, Spain; Institut de Recerca de l’Hospital de laSanta Creu i Sant Pau, Barcelona, SpainCIBER Mental Health (CIBERSAM), Madrid, SpainCIBER Mental Health (CIBERSAM), Madrid, SpainCIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain; Institut de Recerca Sant Joan de Déu, Parc Sanitari Sant Joan de Déu, Barcelona, SpainCIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain; Institute of Biomedicine (IBIOMED), University of Leon, Leon, SpainCIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain; Health Services Research Group, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain; Department of Medicine and Life Sciences, Universitat Pompeu Fabra (UPF), Barcelona, SpainSummary: Background: The 8-item version of the Patient Health Questionnaire (PHQ-8) is one of the self-reported questionnaires most frequently used worldwide for the screening and severity assessment of depression. However, in some European countries its reliability is unknown, and it is unclear whether its psychometric properties vary between European countries. Therefore, the aim of this study was to assess the internal structure, reliability and cross-country equivalence of the PHQ-8 in Europe. Methods: All participants from the 27 countries included in the second wave of the European Health Interview Survey (EHIS-2) between 2014 and 2015 with complete information on the PHQ-8 were included (n = 258,888). The internal structure of the PHQ-8 was assessed using confirmatory factor analyses (CFA) for categorical items. Additionally, the reliability of the questionnaire was assessed based on the internal consistency, Item Response Theory information functions, and item-discrimination (using Graded Response Models), and the cross-country equivalence based on multi-group CFA. Findings: The PHQ-8 shows high internal consistency for all countries. The countries in which the PHQ-8 was more reliable were Romania, Bulgaria and Cyprus and less reliable were Iceland, Norway and Austria. The PHQ-8 item with highest discrimination was item 2 (feeling down, depressed, or hopeless) in 24 of the 27 countries. Measurement invariance between countries in Europe was observed from multigroup CFA at the configural, metric and scalar levels. Interpretation: The results from our study, likely the largest study to the date assessing the internal structure, reliability and cross-country comparability of a self-reported mental health assessment measure, shows that the PHQ-8 has an adequate reliability and cross-country equivalence across the 27 European countries included. These results highlight the suitability of the comparisons of the PHQ-8 scores in Europe. They could be helpful to improve the screening and severity assessment of depressive symptoms at the European level. Funding: This work was partially funded by CIBER Epidemiology and Public Health (CIBERESP) as part of the Intramural call of 2021 (ESP21PI05).http://www.sciencedirect.com/science/article/pii/S2666776223000789DepressionPatient Health QuestionnaireEuropeReliabilityValidityHealth surveys
spellingShingle Jorge Arias de la Torre
Gemma Vilagut
Amy Ronaldson
Jose M. Valderas
Ioannis Bakolis
Alex Dregan
Antonio J. Molina
Fernando Navarro-Mateu
Katherine Pérez
Xavier Bartoll-Roca
Matilde Elices
Víctor Pérez-Sola
Antoni Serrano-Blanco
Vicente Martín
Jordi Alonso
Reliability and cross-country equivalence of the 8-item version of the Patient Health Questionnaire (PHQ-8) for the assessment of depression: results from 27 countries in EuropeResearch in context
The Lancet Regional Health. Europe
Depression
Patient Health Questionnaire
Europe
Reliability
Validity
Health surveys
title Reliability and cross-country equivalence of the 8-item version of the Patient Health Questionnaire (PHQ-8) for the assessment of depression: results from 27 countries in EuropeResearch in context
title_full Reliability and cross-country equivalence of the 8-item version of the Patient Health Questionnaire (PHQ-8) for the assessment of depression: results from 27 countries in EuropeResearch in context
title_fullStr Reliability and cross-country equivalence of the 8-item version of the Patient Health Questionnaire (PHQ-8) for the assessment of depression: results from 27 countries in EuropeResearch in context
title_full_unstemmed Reliability and cross-country equivalence of the 8-item version of the Patient Health Questionnaire (PHQ-8) for the assessment of depression: results from 27 countries in EuropeResearch in context
title_short Reliability and cross-country equivalence of the 8-item version of the Patient Health Questionnaire (PHQ-8) for the assessment of depression: results from 27 countries in EuropeResearch in context
title_sort reliability and cross country equivalence of the 8 item version of the patient health questionnaire phq 8 for the assessment of depression results from 27 countries in europeresearch in context
topic Depression
Patient Health Questionnaire
Europe
Reliability
Validity
Health surveys
url http://www.sciencedirect.com/science/article/pii/S2666776223000789
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