Impact of a NDUFC2 Variant on the Occurrence of Acute Coronary Syndromes

Impact of a NDUFC2 Variant on the Occurrence of Acute Coronary Syndromes

BackgroundAmong several potential mechanisms, mitochondrial dysfunction has been proposed to be involved in the pathogenesis of coronary artery disease (CAD). A mitochondrial complex I deficiency severely impairs cardiovascular health and contributes to CAD development. Previous evidence highlighted...

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Bibliographic Details
Main Authors: Giovanna Gallo, Serena Migliarino, Maria Cotugno, Rosita Stanzione, Simone Burocchi, Franca Bianchi, Simona Marchitti, Camillo Autore, Massimo Volpe, Speranza Rubattu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
acute coronary syndrome
genetic
NDUFC2
complex I
mitochondrial dysfunction
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.921244/full

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