Folliculosebaceous Cystic Hamartoma with Spindle Cell Lipomatous and Neural Components
Folliculosebaceous cystic hamartoma is a cutaneous malformation composed of a cystic folliculosebaceous structure associated with mesenchymal elements, generally consisting of fibrous stroma, adipocytes and small vascular channels. We report the case of a 55-year-old female patient with a cutaneous...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Dermatopathology |
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| Online Access: | https://www.mdpi.com/2296-3529/10/3/27 |
| _version_ | 1827726643152551936 |
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| author | Carmelo Urso Marina Yarygina |
| author_facet | Carmelo Urso Marina Yarygina |
| author_sort | Carmelo Urso |
| collection | DOAJ |
| description | Folliculosebaceous cystic hamartoma is a cutaneous malformation composed of a cystic folliculosebaceous structure associated with mesenchymal elements, generally consisting of fibrous stroma, adipocytes and small vascular channels. We report the case of a 55-year-old female patient with a cutaneous nodule of the right nasal wing. Microscopically, the lesion showed a dilated hair follicle with multiple sebaceous glands, surrounded by a mesenchymal component composed of fibromyxoid stroma, spindle cells, mature-appearing adipocytes and collagen bundles, resembling spindle cell lipoma, associated with an additional neural component, consisting of small nerve bundles. In folliculosebaceous cystic hamartoma, the association of spindle cell lipomatous and neural components has not previously reported. |
| first_indexed | 2024-03-10T22:53:46Z |
| format | Article |
| id | doaj.art-f7e6333a900247b9b6ed30bb1293f36f |
| institution | Directory Open Access Journal |
| issn | 2296-3529 |
| language | English |
| last_indexed | 2024-03-10T22:53:46Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Dermatopathology |
| spelling | doaj.art-f7e6333a900247b9b6ed30bb1293f36f2023-11-19T10:12:17ZengMDPI AGDermatopathology2296-35292023-06-0110319320010.3390/dermatopathology10030027Folliculosebaceous Cystic Hamartoma with Spindle Cell Lipomatous and Neural ComponentsCarmelo Urso0Marina Yarygina1Dermatopathology Study Center of Florence, I-50129 Florence, ItalySynlab Italia, I-25014 Castenedolo, ItalyFolliculosebaceous cystic hamartoma is a cutaneous malformation composed of a cystic folliculosebaceous structure associated with mesenchymal elements, generally consisting of fibrous stroma, adipocytes and small vascular channels. We report the case of a 55-year-old female patient with a cutaneous nodule of the right nasal wing. Microscopically, the lesion showed a dilated hair follicle with multiple sebaceous glands, surrounded by a mesenchymal component composed of fibromyxoid stroma, spindle cells, mature-appearing adipocytes and collagen bundles, resembling spindle cell lipoma, associated with an additional neural component, consisting of small nerve bundles. In folliculosebaceous cystic hamartoma, the association of spindle cell lipomatous and neural components has not previously reported.https://www.mdpi.com/2296-3529/10/3/27folliculosebaceous cystic hamartomaspindle cell lipomanervefollicular tumorshamartomas |
| spellingShingle | Carmelo Urso Marina Yarygina Folliculosebaceous Cystic Hamartoma with Spindle Cell Lipomatous and Neural Components Dermatopathology folliculosebaceous cystic hamartoma spindle cell lipoma nerve follicular tumors hamartomas |
| title | Folliculosebaceous Cystic Hamartoma with Spindle Cell Lipomatous and Neural Components |
| title_full | Folliculosebaceous Cystic Hamartoma with Spindle Cell Lipomatous and Neural Components |
| title_fullStr | Folliculosebaceous Cystic Hamartoma with Spindle Cell Lipomatous and Neural Components |
| title_full_unstemmed | Folliculosebaceous Cystic Hamartoma with Spindle Cell Lipomatous and Neural Components |
| title_short | Folliculosebaceous Cystic Hamartoma with Spindle Cell Lipomatous and Neural Components |
| title_sort | folliculosebaceous cystic hamartoma with spindle cell lipomatous and neural components |
| topic | folliculosebaceous cystic hamartoma spindle cell lipoma nerve follicular tumors hamartomas |
| url | https://www.mdpi.com/2296-3529/10/3/27 |
| work_keys_str_mv | AT carmelourso folliculosebaceouscystichamartomawithspindlecelllipomatousandneuralcomponents AT marinayarygina folliculosebaceouscystichamartomawithspindlecelllipomatousandneuralcomponents |