mRNA‐based Vaccines Targeting the T‐cell Epitope‐rich Domain of Epstein Barr Virus Latent Proteins Elicit Robust Anti‐Tumor Immunity in Mice

mRNA‐based Vaccines Targeting the T‐cell Epitope‐rich Domain of Epstein Barr Virus Latent Proteins Elicit Robust Anti‐Tumor Immunity in Mice

Abstract Epstein‐Barr virus (EBV) is associated with various malignancies and infects >90% of the global population. EBV latent proteins are expressed in numerous EBV‐associated cancers and contribute to carcinogenesis, making them critical therapeutic targets for these cancers. Thus, this study...

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Bibliographic Details
Main Authors: Ge‐Xin Zhao, Guo‐Long Bu, Gang‐Feng Liu, Xiang‐Wei Kong, Cong Sun, Zi‐Qian Li, Dan‐Ling Dai, Hai‐Xia Sun, Yin‐Feng Kang, Guo‐Kai Feng, Qian Zhong, Mu‐Sheng Zeng
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Advanced Science
Subjects:
cancer immunotherapies
Epstein‐Barr virus (EBV)
mRNA vaccines
nasopharyngeal carcinoma (NPC)
Online Access:https://doi.org/10.1002/advs.202302116

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