ACBD3 Is an Essential Pan-enterovirus Host Factor That Mediates the Interaction between Viral 3A Protein and Cellular Protein PI4KB

ACBD3 Is an Essential Pan-enterovirus Host Factor That Mediates the Interaction between Viral 3A Protein and Cellular Protein PI4KB

ABSTRACT The enterovirus genus of the picornavirus family includes a large number of important human pathogens such as poliovirus, coxsackievirus, enterovirus A71, and rhinoviruses. Like all other positive-strand RNA viruses, genome replication of enteroviruses occurs on rearranged membranous struct...

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Bibliographic Details
Main Authors: Heyrhyoung Lyoo, Hilde M. van der Schaar, Cristina M. Dorobantu, Huib H. Rabouw, Jeroen R. P. M. Strating, Frank J. M. van Kuppeveld
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mBio
Subjects:
acyl-coenzyme A binding domain containing 3 (ACBD3)
phosphatidylinositol 4-kinase IIIβ (PI4KB)
enterovirus
replication organelles
viral replication
virus-host interactions
Online Access:https://journals.asm.org/doi/10.1128/mBio.02742-18

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