The spoke wheel color Doppler blood flow signal is a specific sign of papillary thyroid carcinoma
BackgroundPapillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Grayscale ultrasound (US) is the main method used to diagnose benign and malignant thyroid nodules, While color doppler blood flow imaging(CDFI) is not widely recognized when diagnosing thyroid cancer.MethodsThis...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.1030143/full |
| _version_ | 1811338623220449280 |
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| author | Nianyu Xue Ping Li Huadong Deng Jing Yi Yu Xie Shengmin Zhang |
| author_facet | Nianyu Xue Ping Li Huadong Deng Jing Yi Yu Xie Shengmin Zhang |
| author_sort | Nianyu Xue |
| collection | DOAJ |
| description | BackgroundPapillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Grayscale ultrasound (US) is the main method used to diagnose benign and malignant thyroid nodules, While color doppler blood flow imaging(CDFI) is not widely recognized when diagnosing thyroid cancer.MethodsThis study used a retrospective analysis. The study included 36 spoked wheel blood flow nodules detected by CDFI in 37,372 patients in five hospitals from January 2020 to June 2021. All thyroid nodules were examined histologically after ultrasound-guided fine needle biopsy or following surgical resection. The value of color doppler in diagnosing papillary thyroid carcinoma was evaluated based on pathological results.ResultsAmong 36 thyroid nodules, only 6 were highly suspected of being malignant on grayscale ultrasound (classified as 5, according to ACR TI-RADS). However, these 36 thyroid nodules showed spoke wheel blood flow signal distribution on CDFI. If the spoke wheel blood flow signal is used to diagnose papillary thyroid cancer, then the diagnostic accuracy of this group of papillary thyroid cancers can reach 100%, which is significantly higher than the accuracy of grayscale ultrasound diagnosis, and the difference is statistically significant (p<0.05).ConclusionsThe results of this study found that spoke wheel blood flow sign on CDFI can be used to diagnose PTC. PTC with spoke wheel blood flow have benign characteristics on gray-scale ultrasound, which is easy to be misdiagnosed. |
| first_indexed | 2024-04-13T18:13:51Z |
| format | Article |
| id | doaj.art-f7e93b3d87bf4e39ac3d1fd84a524182 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-13T18:13:51Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-f7e93b3d87bf4e39ac3d1fd84a5241822022-12-22T02:35:46ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-10-011310.3389/fendo.2022.10301431030143The spoke wheel color Doppler blood flow signal is a specific sign of papillary thyroid carcinomaNianyu Xue0Ping Li1Huadong Deng2Jing Yi3Yu Xie4Shengmin Zhang5Department of Ultrasonography, Ningbo First Hospital, Ningbo, Zhejiang, ChinaDepartment of Ultrasonography, Nanjing First Hospital, Jiangsu, ChinaDepartment of Ultrasonography, Lishui People's Hospital, Zhejiang, ChinaDepartment of Ultrasonography, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, ChinaDepartment of Ultrasonography, Meishan People’s Hospital, Meishan, ChinaDepartment of Ultrasonography, Ningbo First Hospital, Ningbo, Zhejiang, ChinaBackgroundPapillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Grayscale ultrasound (US) is the main method used to diagnose benign and malignant thyroid nodules, While color doppler blood flow imaging(CDFI) is not widely recognized when diagnosing thyroid cancer.MethodsThis study used a retrospective analysis. The study included 36 spoked wheel blood flow nodules detected by CDFI in 37,372 patients in five hospitals from January 2020 to June 2021. All thyroid nodules were examined histologically after ultrasound-guided fine needle biopsy or following surgical resection. The value of color doppler in diagnosing papillary thyroid carcinoma was evaluated based on pathological results.ResultsAmong 36 thyroid nodules, only 6 were highly suspected of being malignant on grayscale ultrasound (classified as 5, according to ACR TI-RADS). However, these 36 thyroid nodules showed spoke wheel blood flow signal distribution on CDFI. If the spoke wheel blood flow signal is used to diagnose papillary thyroid cancer, then the diagnostic accuracy of this group of papillary thyroid cancers can reach 100%, which is significantly higher than the accuracy of grayscale ultrasound diagnosis, and the difference is statistically significant (p<0.05).ConclusionsThe results of this study found that spoke wheel blood flow sign on CDFI can be used to diagnose PTC. PTC with spoke wheel blood flow have benign characteristics on gray-scale ultrasound, which is easy to be misdiagnosed.https://www.frontiersin.org/articles/10.3389/fendo.2022.1030143/fullthyroid neoplasmsultrasonographydopplercolorpapillary thyroid carcinoma |
| spellingShingle | Nianyu Xue Ping Li Huadong Deng Jing Yi Yu Xie Shengmin Zhang The spoke wheel color Doppler blood flow signal is a specific sign of papillary thyroid carcinoma Frontiers in Endocrinology thyroid neoplasms ultrasonography doppler color papillary thyroid carcinoma |
| title | The spoke wheel color Doppler blood flow signal is a specific sign of papillary thyroid carcinoma |
| title_full | The spoke wheel color Doppler blood flow signal is a specific sign of papillary thyroid carcinoma |
| title_fullStr | The spoke wheel color Doppler blood flow signal is a specific sign of papillary thyroid carcinoma |
| title_full_unstemmed | The spoke wheel color Doppler blood flow signal is a specific sign of papillary thyroid carcinoma |
| title_short | The spoke wheel color Doppler blood flow signal is a specific sign of papillary thyroid carcinoma |
| title_sort | spoke wheel color doppler blood flow signal is a specific sign of papillary thyroid carcinoma |
| topic | thyroid neoplasms ultrasonography doppler color papillary thyroid carcinoma |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2022.1030143/full |
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