On the Fate of Butyl Methoxydibenzoylmethane (Avobenzone) in Coral Tissue and Its Effect on Coral Metabolome
The intensive use of sunscreen products has raised concerns regarding their environmental toxicity and the adverse impacts of ultraviolet (UV) filters on ecologically important coral communities. Prior metabolomic analyses on symbiotic coral <i>Pocillopora damicornis</i> exposed to the U...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Metabolites |
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| Online Access: | https://www.mdpi.com/2218-1989/13/4/533 |
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| author | Fanny Clergeaud Maeva Giraudo Alice M. S. Rodrigues Evane Thorel Philippe Lebaron Didier Stien |
| author_facet | Fanny Clergeaud Maeva Giraudo Alice M. S. Rodrigues Evane Thorel Philippe Lebaron Didier Stien |
| author_sort | Fanny Clergeaud |
| collection | DOAJ |
| description | The intensive use of sunscreen products has raised concerns regarding their environmental toxicity and the adverse impacts of ultraviolet (UV) filters on ecologically important coral communities. Prior metabolomic analyses on symbiotic coral <i>Pocillopora damicornis</i> exposed to the UV filter butyl methoxydibenzoylmethane (BM, avobenzone) revealed unidentified ions in the holobiont metabolome. In the present study, follow-up differential metabolomic analyses in BM-exposed <i>P. damicornis</i> detected 57 ions with significantly different relative concentrations in exposed corals. The results showed an accumulation of 17 BM derivatives produced through BM reduction and esterification. The major derivative identified C16:0-dihydroBM, which was synthesized and used as a standard to quantify BM derivatives in coral extracts. The results indicated that relative amounts of BM derivatives made up to 95% of the total BM (<i>w</i>/<i>w</i>) absorbed in coral tissue after 7 days of exposure. Among the remaining metabolites annotated, seven compounds significantly affected by BM exposure could be attributed to the coral dinoflagellate symbiont, indicating that BM exposure might impair the photosynthetic capacity of the holobiont. The present results suggest that the potential role of BM in coral bleaching in anthropogenic areas should be investigated and that BM derivatives should be considered in future assessments on the fate and effects of BM in the environment. |
| first_indexed | 2024-03-11T04:46:13Z |
| format | Article |
| id | doaj.art-f7e9f68686744d4185942f68da82be74 |
| institution | Directory Open Access Journal |
| issn | 2218-1989 |
| language | English |
| last_indexed | 2024-03-11T04:46:13Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Metabolites |
| spelling | doaj.art-f7e9f68686744d4185942f68da82be742023-11-17T20:24:50ZengMDPI AGMetabolites2218-19892023-04-0113453310.3390/metabo13040533On the Fate of Butyl Methoxydibenzoylmethane (Avobenzone) in Coral Tissue and Its Effect on Coral MetabolomeFanny Clergeaud0Maeva Giraudo1Alice M. S. Rodrigues2Evane Thorel3Philippe Lebaron4Didier Stien5Sorbonne Université, CNRS, Laboratoire de Biodiversité et Biotechnologies Microbiennes, UAR3579, Observatoire Océanologique, 66650 Banyuls-sur-Mer, FranceSorbonne Université, CNRS, Laboratoire de Biodiversité et Biotechnologies Microbiennes, UAR3579, Observatoire Océanologique, 66650 Banyuls-sur-Mer, FranceSorbonne Université, CNRS, Laboratoire de Biodiversité et Biotechnologies Microbiennes, UAR3579, Observatoire Océanologique, 66650 Banyuls-sur-Mer, FranceSorbonne Université, CNRS, Laboratoire de Biodiversité et Biotechnologies Microbiennes, UAR3579, Observatoire Océanologique, 66650 Banyuls-sur-Mer, FranceSorbonne Université, CNRS, Laboratoire de Biodiversité et Biotechnologies Microbiennes, UAR3579, Observatoire Océanologique, 66650 Banyuls-sur-Mer, FranceSorbonne Université, CNRS, Laboratoire de Biodiversité et Biotechnologies Microbiennes, UAR3579, Observatoire Océanologique, 66650 Banyuls-sur-Mer, FranceThe intensive use of sunscreen products has raised concerns regarding their environmental toxicity and the adverse impacts of ultraviolet (UV) filters on ecologically important coral communities. Prior metabolomic analyses on symbiotic coral <i>Pocillopora damicornis</i> exposed to the UV filter butyl methoxydibenzoylmethane (BM, avobenzone) revealed unidentified ions in the holobiont metabolome. In the present study, follow-up differential metabolomic analyses in BM-exposed <i>P. damicornis</i> detected 57 ions with significantly different relative concentrations in exposed corals. The results showed an accumulation of 17 BM derivatives produced through BM reduction and esterification. The major derivative identified C16:0-dihydroBM, which was synthesized and used as a standard to quantify BM derivatives in coral extracts. The results indicated that relative amounts of BM derivatives made up to 95% of the total BM (<i>w</i>/<i>w</i>) absorbed in coral tissue after 7 days of exposure. Among the remaining metabolites annotated, seven compounds significantly affected by BM exposure could be attributed to the coral dinoflagellate symbiont, indicating that BM exposure might impair the photosynthetic capacity of the holobiont. The present results suggest that the potential role of BM in coral bleaching in anthropogenic areas should be investigated and that BM derivatives should be considered in future assessments on the fate and effects of BM in the environment.https://www.mdpi.com/2218-1989/13/4/533marine ecotoxicityenvironmental fatepersonal care products<i>Pocillopora damicornis</i>avobenzoneSymbiodiniaceae |
| spellingShingle | Fanny Clergeaud Maeva Giraudo Alice M. S. Rodrigues Evane Thorel Philippe Lebaron Didier Stien On the Fate of Butyl Methoxydibenzoylmethane (Avobenzone) in Coral Tissue and Its Effect on Coral Metabolome Metabolites marine ecotoxicity environmental fate personal care products <i>Pocillopora damicornis</i> avobenzone Symbiodiniaceae |
| title | On the Fate of Butyl Methoxydibenzoylmethane (Avobenzone) in Coral Tissue and Its Effect on Coral Metabolome |
| title_full | On the Fate of Butyl Methoxydibenzoylmethane (Avobenzone) in Coral Tissue and Its Effect on Coral Metabolome |
| title_fullStr | On the Fate of Butyl Methoxydibenzoylmethane (Avobenzone) in Coral Tissue and Its Effect on Coral Metabolome |
| title_full_unstemmed | On the Fate of Butyl Methoxydibenzoylmethane (Avobenzone) in Coral Tissue and Its Effect on Coral Metabolome |
| title_short | On the Fate of Butyl Methoxydibenzoylmethane (Avobenzone) in Coral Tissue and Its Effect on Coral Metabolome |
| title_sort | on the fate of butyl methoxydibenzoylmethane avobenzone in coral tissue and its effect on coral metabolome |
| topic | marine ecotoxicity environmental fate personal care products <i>Pocillopora damicornis</i> avobenzone Symbiodiniaceae |
| url | https://www.mdpi.com/2218-1989/13/4/533 |
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