Dissociation Constant of Integrin-RGD Binding in Live Cells from Automated Micropipette and Label-Free Optical Data

Dissociation Constant of Integrin-RGD Binding in Live Cells from Automated Micropipette and Label-Free Optical Data

The binding of integrin proteins to peptide sequences such as arginine-glycine-aspartic acid (RGD) is a crucial step in the adhesion process of mammalian cells. While these bonds can be examined between purified proteins and their ligands, live-cell assays are better suited to gain biologically rele...

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Bibliographic Details
Main Authors: Tamás Gerecsei, Péter Chrenkó, Nicolett Kanyo, Beatrix Péter, Attila Bonyár, Inna Székács, Balint Szabo, Robert Horvath
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biosensors
Subjects:
adhesion
micropipette
waveguide
biosensor
two-dimensional dissociation constant
integrin-RGD-binding
Online Access:https://www.mdpi.com/2079-6374/11/2/32

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