Theta Activity in the Left Dorsal Premotor Cortex During Action Re-Evaluation and Motor Reprogramming
The ability to rapidly adjust our actions to changes in the environment is a key function of human motor control. Previous work implicated the dorsal premotor cortex (dPMC) in the up-dating of action plans based on environmental cues. Here we used electroencephalography (EEG) to identify neural sign...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-09-01
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| Series: | Frontiers in Human Neuroscience |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fnhum.2018.00364/full |
| _version_ | 1819006708547059712 |
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| author | Giovanni Pellegrino Giovanni Pellegrino Leo Tomasevic Damian Marc Herz Damian Marc Herz Kit Melissa Larsen Kit Melissa Larsen Hartwig Roman Siebner Hartwig Roman Siebner |
| author_facet | Giovanni Pellegrino Giovanni Pellegrino Leo Tomasevic Damian Marc Herz Damian Marc Herz Kit Melissa Larsen Kit Melissa Larsen Hartwig Roman Siebner Hartwig Roman Siebner |
| author_sort | Giovanni Pellegrino |
| collection | DOAJ |
| description | The ability to rapidly adjust our actions to changes in the environment is a key function of human motor control. Previous work implicated the dorsal premotor cortex (dPMC) in the up-dating of action plans based on environmental cues. Here we used electroencephalography (EEG) to identify neural signatures of up-dating cue-action relationships in the dPMC and connected frontoparietal areas. Ten healthy subjects performed a pre-cued alternate choice task. Simple geometric shapes cued button presses with the right or left index finger. The shapes of the pre-cue and go-cue differed in two third of trials. In these incongruent trials, the go-cue prompted a re-evaluation of the pre-cued action plan, slowing response time relative to trials with identical cues. This re-evaluation selectively increased theta band activity without modifying activity in alpha and beta band. Source-based analysis revealed a widespread theta increase in dorsal and mesial frontoparietal areas, including dPMC, supplementary motor area (SMA), primary motor and posterior parietal cortices (PPC). Theta activity scaled positively with response slowing and increased more strongly when the pre-cue was invalid and required subjects to select the alternate response. Together, the results indicate that theta activity in dPMC and connected frontoparietal areas is involved in the re-adjustment of cue-induced action tendencies. |
| first_indexed | 2024-12-21T00:12:59Z |
| format | Article |
| id | doaj.art-f7f547339f5d43f4b5921afa2fcea273 |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-12-21T00:12:59Z |
| publishDate | 2018-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-f7f547339f5d43f4b5921afa2fcea2732022-12-21T19:22:19ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612018-09-011210.3389/fnhum.2018.00364383560Theta Activity in the Left Dorsal Premotor Cortex During Action Re-Evaluation and Motor ReprogrammingGiovanni Pellegrino0Giovanni Pellegrino1Leo Tomasevic2Damian Marc Herz3Damian Marc Herz4Kit Melissa Larsen5Kit Melissa Larsen6Hartwig Roman Siebner7Hartwig Roman Siebner8Danish Research Centre for Magnetic Resonance (DRCMR), Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Hvidovre, DenmarkSan Camillo Hospital IRCCS, Venice, ItalyDanish Research Centre for Magnetic Resonance (DRCMR), Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Hvidovre, DenmarkDanish Research Centre for Magnetic Resonance (DRCMR), Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Hvidovre, DenmarkDepartment of Neurology, Copenhagen University Hospital Bispebjerg, Copenhagen, DenmarkDanish Research Centre for Magnetic Resonance (DRCMR), Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Hvidovre, DenmarkQueensland Brain Institute, The University of Queensland, Brisbane, QLD, AustraliaDanish Research Centre for Magnetic Resonance (DRCMR), Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Hvidovre, DenmarkDepartment of Neurology, Copenhagen University Hospital Bispebjerg, Copenhagen, DenmarkThe ability to rapidly adjust our actions to changes in the environment is a key function of human motor control. Previous work implicated the dorsal premotor cortex (dPMC) in the up-dating of action plans based on environmental cues. Here we used electroencephalography (EEG) to identify neural signatures of up-dating cue-action relationships in the dPMC and connected frontoparietal areas. Ten healthy subjects performed a pre-cued alternate choice task. Simple geometric shapes cued button presses with the right or left index finger. The shapes of the pre-cue and go-cue differed in two third of trials. In these incongruent trials, the go-cue prompted a re-evaluation of the pre-cued action plan, slowing response time relative to trials with identical cues. This re-evaluation selectively increased theta band activity without modifying activity in alpha and beta band. Source-based analysis revealed a widespread theta increase in dorsal and mesial frontoparietal areas, including dPMC, supplementary motor area (SMA), primary motor and posterior parietal cortices (PPC). Theta activity scaled positively with response slowing and increased more strongly when the pre-cue was invalid and required subjects to select the alternate response. Together, the results indicate that theta activity in dPMC and connected frontoparietal areas is involved in the re-adjustment of cue-induced action tendencies.https://www.frontiersin.org/article/10.3389/fnhum.2018.00364/fullaction selectionmotor reprogrammingthetaEEGdorsal premotor cortexmotor |
| spellingShingle | Giovanni Pellegrino Giovanni Pellegrino Leo Tomasevic Damian Marc Herz Damian Marc Herz Kit Melissa Larsen Kit Melissa Larsen Hartwig Roman Siebner Hartwig Roman Siebner Theta Activity in the Left Dorsal Premotor Cortex During Action Re-Evaluation and Motor Reprogramming Frontiers in Human Neuroscience action selection motor reprogramming theta EEG dorsal premotor cortex motor |
| title | Theta Activity in the Left Dorsal Premotor Cortex During Action Re-Evaluation and Motor Reprogramming |
| title_full | Theta Activity in the Left Dorsal Premotor Cortex During Action Re-Evaluation and Motor Reprogramming |
| title_fullStr | Theta Activity in the Left Dorsal Premotor Cortex During Action Re-Evaluation and Motor Reprogramming |
| title_full_unstemmed | Theta Activity in the Left Dorsal Premotor Cortex During Action Re-Evaluation and Motor Reprogramming |
| title_short | Theta Activity in the Left Dorsal Premotor Cortex During Action Re-Evaluation and Motor Reprogramming |
| title_sort | theta activity in the left dorsal premotor cortex during action re evaluation and motor reprogramming |
| topic | action selection motor reprogramming theta EEG dorsal premotor cortex motor |
| url | https://www.frontiersin.org/article/10.3389/fnhum.2018.00364/full |
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