Trust-Based Decision-Making in the Health Context Discriminates Biological Risk Profiles in Type 1 Diabetes
Theoretical accounts on social decision-making under uncertainty postulate that individual risk preferences are context dependent. Generalization of models of decision-making to dyadic interactions in the personal health context remain to be experimentally addressed. In economic utility-based models...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/12/8/1236 |
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| author | Helena Jorge Isabel C. Duarte Carla Baptista Ana Paula Relvas Miguel Castelo-Branco |
| author_facet | Helena Jorge Isabel C. Duarte Carla Baptista Ana Paula Relvas Miguel Castelo-Branco |
| author_sort | Helena Jorge |
| collection | DOAJ |
| description | Theoretical accounts on social decision-making under uncertainty postulate that individual risk preferences are context dependent. Generalization of models of decision-making to dyadic interactions in the personal health context remain to be experimentally addressed. In economic utility-based models, interactive behavioral games provide a framework to investigate probabilistic learning of sequential reinforcement. Here, we model an economic trust game in the context of a chronic disease (Diabetes Type 1) which involves iterated daily decisions in complex social contexts. Ninety-one patients performed experimental trust games in both economic and health settings and were characterized by a multiple self-report set of questionnaires. We found that although our groups can correctly infer pay-off contingencies, they behave differently because patients with a biological profile of preserved glycemic control show adaptive choice behavior both in economic and health domains. On the other hand, patients with a biological profile of loss of glycemic control presented a contrasting behavior, showing non-adaptive choices on both contexts. These results provide a direct translation from neuroeconomics to decision-making in the health domain and biological risk profiles, in a behavioral setting that requires difficult and self-consequential decisions with health impact. Our findings also provide a contextual generalization of mechanisms underlying individual decision-making under uncertainty. |
| first_indexed | 2024-03-09T13:08:13Z |
| format | Article |
| id | doaj.art-f7f83ba506b249959fb41ec0921ea882 |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-09T13:08:13Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-f7f83ba506b249959fb41ec0921ea8822023-11-30T21:45:51ZengMDPI AGJournal of Personalized Medicine2075-44262022-07-01128123610.3390/jpm12081236Trust-Based Decision-Making in the Health Context Discriminates Biological Risk Profiles in Type 1 DiabetesHelena Jorge0Isabel C. Duarte1Carla Baptista2Ana Paula Relvas3Miguel Castelo-Branco4Coimbra Institute for Biomedical Imaging and Translational Research, CIBIT/ICNAS, Faculty of Medicine, University of Coimbra, 3004-531 Coimbra, PortugalCoimbra Institute for Biomedical Imaging and Translational Research, CIBIT/ICNAS, Faculty of Medicine, University of Coimbra, 3004-531 Coimbra, PortugalEndocrinology, Diabetes and Metabolism Department (SEMD), University and Hospital Center of Coimbra, 3004-561 Coimbra, PortugalFaculty of Psychology and Educational Sciences & Center for Social Studies, University of Coimbra, 3004-531 Coimbra, PortugalCoimbra Institute for Biomedical Imaging and Translational Research, CIBIT/ICNAS, Faculty of Medicine, University of Coimbra, 3004-531 Coimbra, PortugalTheoretical accounts on social decision-making under uncertainty postulate that individual risk preferences are context dependent. Generalization of models of decision-making to dyadic interactions in the personal health context remain to be experimentally addressed. In economic utility-based models, interactive behavioral games provide a framework to investigate probabilistic learning of sequential reinforcement. Here, we model an economic trust game in the context of a chronic disease (Diabetes Type 1) which involves iterated daily decisions in complex social contexts. Ninety-one patients performed experimental trust games in both economic and health settings and were characterized by a multiple self-report set of questionnaires. We found that although our groups can correctly infer pay-off contingencies, they behave differently because patients with a biological profile of preserved glycemic control show adaptive choice behavior both in economic and health domains. On the other hand, patients with a biological profile of loss of glycemic control presented a contrasting behavior, showing non-adaptive choices on both contexts. These results provide a direct translation from neuroeconomics to decision-making in the health domain and biological risk profiles, in a behavioral setting that requires difficult and self-consequential decisions with health impact. Our findings also provide a contextual generalization of mechanisms underlying individual decision-making under uncertainty.https://www.mdpi.com/2075-4426/12/8/1236human decision-makingdiabetes type 1context-dependent trust gameprobabilistic learningnorm violationtreatment adherence |
| spellingShingle | Helena Jorge Isabel C. Duarte Carla Baptista Ana Paula Relvas Miguel Castelo-Branco Trust-Based Decision-Making in the Health Context Discriminates Biological Risk Profiles in Type 1 Diabetes Journal of Personalized Medicine human decision-making diabetes type 1 context-dependent trust game probabilistic learning norm violation treatment adherence |
| title | Trust-Based Decision-Making in the Health Context Discriminates Biological Risk Profiles in Type 1 Diabetes |
| title_full | Trust-Based Decision-Making in the Health Context Discriminates Biological Risk Profiles in Type 1 Diabetes |
| title_fullStr | Trust-Based Decision-Making in the Health Context Discriminates Biological Risk Profiles in Type 1 Diabetes |
| title_full_unstemmed | Trust-Based Decision-Making in the Health Context Discriminates Biological Risk Profiles in Type 1 Diabetes |
| title_short | Trust-Based Decision-Making in the Health Context Discriminates Biological Risk Profiles in Type 1 Diabetes |
| title_sort | trust based decision making in the health context discriminates biological risk profiles in type 1 diabetes |
| topic | human decision-making diabetes type 1 context-dependent trust game probabilistic learning norm violation treatment adherence |
| url | https://www.mdpi.com/2075-4426/12/8/1236 |
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