Fast, In Vivo Model for Drug-Response Prediction in Patients with B-Cell Precursor Acute Lymphoblastic Leukemia
Only half of patients with relapsed B-cell precursor (BCP) acute lymphoblastic leukemia (ALL) currently survive with standard treatment protocols. Predicting individual patient responses to defined drugs prior to application would help therapy stratification and could improve survival. With the purp...
Main Authors: | Anton Gauert, Nadine Olk, Helia Pimentel-Gutiérrez, Kathy Astrahantseff, Lasse D. Jensen, Yihai Cao, Angelika Eggert, Cornelia Eckert, Anja I.H. Hagemann |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-07-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/12/7/1883 |
Similar Items
-
Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo
by: Dorothee Winterberg, et al.
Published: (2021-06-01) -
Pediatric Precursor B-Cell Lymphoblastic Malignancies: From Extramedullary to Medullary Involvement
by: Emma Kroeze, et al.
Published: (2022-08-01) -
DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia
by: Magnus Borssén, et al.
Published: (2018-03-01) -
Multi-Faceted Effects of ST6Gal1 Expression on Precursor B-Lineage Acute Lymphoblastic Leukemia
by: Mingfeng Zhang, et al.
Published: (2022-03-01) -
Added value of molecular karyotype in childhood acute lymphoblastic leukemia
by: Margaux Camuset, et al.
Published: (2023-12-01)