Neuronal Pnn Deficiency Increases Oxidative Stress and Exacerbates Cerebral Ischemia/Reperfusion Injury in Mice

Neuronal Pnn Deficiency Increases Oxidative Stress and Exacerbates Cerebral Ischemia/Reperfusion Injury in Mice

Cerebral stroke remains one of the leading causes of death worldwide. Ischemic stroke caused by the sudden loss of blood flow in brain is the major type of cerebral stroke. In addition to necrotic cell death in the ischemic core region, neuronal apoptosis is usually observed in the ischemic penumbra...

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Bibliographic Details
Main Authors: Shu-Yuan Hsu, Chih-Hung Chen, Sujira Mukda, Steve Leu
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Antioxidants
Subjects:
Pnn
neuron
ischemia/reperfusion
mRNA alternative splicing
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/11/3/466

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