The COPD Assessment Test (CAT) and Depression: A Longitudinal Analysis During the COVID-19 Pandemic
Augusta Beech,1,2 Dave Singh1,2 1Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; 2Medicines Evaluation Unit, Manchester Universit...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-06-01
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| Series: | International Journal of COPD |
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| Online Access: | https://www.dovepress.com/the-copd-assessment-test-cat-and-depression-a-longitudinal-analysis-du-peer-reviewed-fulltext-article-COPD |
| _version_ | 1797789468191621120 |
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| author | Beech A Singh D |
| author_facet | Beech A Singh D |
| author_sort | Beech A |
| collection | DOAJ |
| description | Augusta Beech,1,2 Dave Singh1,2 1Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; 2Medicines Evaluation Unit, Manchester University NHS Foundation Trust, Manchester, UKCorrespondence: Augusta Beech, Department of Medicine and Health, University of Manchester, Education and Research Centre, Manchester, M23 9LT, UK, Tel +44 161 946 4050, Fax +44 161 946 1459, Email augusta.beech@manchester.ac.ukPurpose: Chronic obstructive pulmonary disease (COPD) is multifaceted, with some patients experiencing anxiety and depression. Depression in COPD has been associated with worse total scores for the COPD assessment test (CAT). Also, CAT score worsening has been observed during the COVID-19 pandemic. The relationship between the Center for Epidemiologic Studies Depression Scale (CES-D) score and CAT sub-component scores has not been evaluated. We investigated the relationship between CES-D score and CAT component scores during the COVD-19 pandemic.Patients and Methods: Sixty-five patients were recruited. Pre-pandemic (baseline) was defined as 23rd March 2019– 23rd March 2020, CAT scores and information related to exacerbations were collected via telephone at 8-week intervals between 23rd March 2020– 23rd March 2021.Results: There were no differences in CAT scores pre- compared to during the pandemic (ANOVA p = 0.97). Total CAT scores were higher in patients with symptoms of depression compared to those without both pre- (p < 0.001) and during-pandemic (eg, at 12 months 21.2 versus 12.9, mean difference = 8.3 (95% CI = 2.3– 14.2), p = 0.02). Individual CAT component scores showed significantly higher chest tightness, breathlessness, activity limitation, confidence, sleep and energy scores in patients with symptoms of depression at most time points (p < 0.05). Significantly fewer exacerbations were observed during- compared to pre-pandemic (p = 0.04). We observed that COPD patients with symptoms of depression had higher CAT scores both pre- and during the COVID-19 pandemic.Conclusion: Presence of depressive symptoms was selectively associated with individual component scores. Symptoms of depression may potentially influence total CAT scores.Keywords: COPD, depression, COPD assessment test, CAT, center for epidemiological studies depression score, CES-D |
| first_indexed | 2024-03-13T01:51:05Z |
| format | Article |
| id | doaj.art-f80282e0f61a4537bc67204ae2b639f6 |
| institution | Directory Open Access Journal |
| issn | 1178-2005 |
| language | English |
| last_indexed | 2024-03-13T01:51:05Z |
| publishDate | 2023-06-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of COPD |
| spelling | doaj.art-f80282e0f61a4537bc67204ae2b639f62023-07-02T19:49:15ZengDove Medical PressInternational Journal of COPD1178-20052023-06-01Volume 181187119584402The COPD Assessment Test (CAT) and Depression: A Longitudinal Analysis During the COVID-19 PandemicBeech ASingh DAugusta Beech,1,2 Dave Singh1,2 1Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; 2Medicines Evaluation Unit, Manchester University NHS Foundation Trust, Manchester, UKCorrespondence: Augusta Beech, Department of Medicine and Health, University of Manchester, Education and Research Centre, Manchester, M23 9LT, UK, Tel +44 161 946 4050, Fax +44 161 946 1459, Email augusta.beech@manchester.ac.ukPurpose: Chronic obstructive pulmonary disease (COPD) is multifaceted, with some patients experiencing anxiety and depression. Depression in COPD has been associated with worse total scores for the COPD assessment test (CAT). Also, CAT score worsening has been observed during the COVID-19 pandemic. The relationship between the Center for Epidemiologic Studies Depression Scale (CES-D) score and CAT sub-component scores has not been evaluated. We investigated the relationship between CES-D score and CAT component scores during the COVD-19 pandemic.Patients and Methods: Sixty-five patients were recruited. Pre-pandemic (baseline) was defined as 23rd March 2019– 23rd March 2020, CAT scores and information related to exacerbations were collected via telephone at 8-week intervals between 23rd March 2020– 23rd March 2021.Results: There were no differences in CAT scores pre- compared to during the pandemic (ANOVA p = 0.97). Total CAT scores were higher in patients with symptoms of depression compared to those without both pre- (p < 0.001) and during-pandemic (eg, at 12 months 21.2 versus 12.9, mean difference = 8.3 (95% CI = 2.3– 14.2), p = 0.02). Individual CAT component scores showed significantly higher chest tightness, breathlessness, activity limitation, confidence, sleep and energy scores in patients with symptoms of depression at most time points (p < 0.05). Significantly fewer exacerbations were observed during- compared to pre-pandemic (p = 0.04). We observed that COPD patients with symptoms of depression had higher CAT scores both pre- and during the COVID-19 pandemic.Conclusion: Presence of depressive symptoms was selectively associated with individual component scores. Symptoms of depression may potentially influence total CAT scores.Keywords: COPD, depression, COPD assessment test, CAT, center for epidemiological studies depression score, CES-Dhttps://www.dovepress.com/the-copd-assessment-test-cat-and-depression-a-longitudinal-analysis-du-peer-reviewed-fulltext-article-COPDcopddepressioncopd assessment testcatcenter for epidemiological studies depression scoreces-d. |
| spellingShingle | Beech A Singh D The COPD Assessment Test (CAT) and Depression: A Longitudinal Analysis During the COVID-19 Pandemic International Journal of COPD copd depression copd assessment test cat center for epidemiological studies depression score ces-d. |
| title | The COPD Assessment Test (CAT) and Depression: A Longitudinal Analysis During the COVID-19 Pandemic |
| title_full | The COPD Assessment Test (CAT) and Depression: A Longitudinal Analysis During the COVID-19 Pandemic |
| title_fullStr | The COPD Assessment Test (CAT) and Depression: A Longitudinal Analysis During the COVID-19 Pandemic |
| title_full_unstemmed | The COPD Assessment Test (CAT) and Depression: A Longitudinal Analysis During the COVID-19 Pandemic |
| title_short | The COPD Assessment Test (CAT) and Depression: A Longitudinal Analysis During the COVID-19 Pandemic |
| title_sort | copd assessment test cat and depression a longitudinal analysis during the covid 19 pandemic |
| topic | copd depression copd assessment test cat center for epidemiological studies depression score ces-d. |
| url | https://www.dovepress.com/the-copd-assessment-test-cat-and-depression-a-longitudinal-analysis-du-peer-reviewed-fulltext-article-COPD |
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