SKping cell cycle regulation: role of ubiquitin ligase SKP2 in hematological malignancies

SKping cell cycle regulation: role of ubiquitin ligase SKP2 in hematological malignancies

SKP2 (S-phase kinase-associated protein 2) is a member of the F-box family of substrate-recognition subunits in the SCF ubiquitin-protein ligase complexes. It is associated with ubiquitin-mediated degradation in the mammalian cell cycle components and other target proteins involved in cell cycle pro...

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Bibliographic Details
Main Authors: Jonahunnatha Nesson George William, Ruby Dhar, Rohit Gundamaraju, Om Saswat Sahoo, Karthikeyan Pethusamy, A. F. P. Allwin Mabes Raj, Subbiah Ramasamy, Mohammed S. Alqahtani, Mohamed Abbas, Subhradip Karmakar
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Oncology
Subjects:
AML
leukemia
hematological cancers
miRNA
Skp2
oncogene
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1288501/full

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