Synthesis, Crystal Structures, Lipophilic Properties and Antimicrobial Activity of 5-Pyridylmethylidene-3-rhodanine-carboxyalkyl Acids Derivatives

Synthesis, Crystal Structures, Lipophilic Properties and Antimicrobial Activity of 5-Pyridylmethylidene-3-rhodanine-carboxyalkyl Acids Derivatives

The constant increase in the resistance of pathogenic bacteria to the commonly used drugs so far makes it necessary to search for new substances with antibacterial activity. Taking up this challenge, we obtained a series of rhodanine-3-carboxyalkyl acid derivatives containing 2- or 3- or 4-pyridinyl...

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Bibliographic Details
Main Authors: Ewa Żesławska, Robert Zakrzewski, Arkadiusz Nowicki, Izabela Korona-Głowniak, Antonín Lyčka, Agnieszka Kania, Krzysztof Kazimierz Zborowski, Piotr Suder, Agnieszka Skórska-Stania, Waldemar Tejchman
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
rhodanine
antimicrobial activity
lipophilicity
crystal structure
electron density
N···S interaction
Online Access:https://www.mdpi.com/1420-3049/27/13/3975

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