Regulation of cell adhesion in the testis: a new role for p73
The dramatic changes that male germ cells in the adult testis undergo in gene expression profile and morphology as they transition from spermatogonial stem cells through to mature spermatozoa is dependent upon their association with Sertoli cells. Sertoli cells are crucial for survival and maturatio...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2014-12-01
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| Series: | Asian Journal of Andrology |
| Online Access: | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=6;spage=799;epage=800;aulast=Abud |
| _version_ | 1818011850643603456 |
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| author | Helen E Abud Gary R Hime |
| author_facet | Helen E Abud Gary R Hime |
| author_sort | Helen E Abud |
| collection | DOAJ |
| description | The dramatic changes that male germ cells in the adult testis undergo in gene expression profile and morphology as they transition from spermatogonial stem cells through to mature spermatozoa is dependent upon their association with Sertoli cells. Sertoli cells are crucial for survival and maturation of male germ cells. Two recent papers, Holembowski et al. [1] and Inoue et al. [2] have described a surprising role for the p53 family member, p73, in regulation of germ cell-Sertoli cell adhesion. |
| first_indexed | 2024-04-14T06:13:38Z |
| format | Article |
| id | doaj.art-f80669a45f8949c8b5056df6811d7e50 |
| institution | Directory Open Access Journal |
| issn | 1008-682X 1745-7262 |
| language | English |
| last_indexed | 2024-04-14T06:13:38Z |
| publishDate | 2014-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Andrology |
| spelling | doaj.art-f80669a45f8949c8b5056df6811d7e502022-12-22T02:08:18ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622014-12-0116679980010.4103/1008-682X.133315Regulation of cell adhesion in the testis: a new role for p73Helen E AbudGary R HimeThe dramatic changes that male germ cells in the adult testis undergo in gene expression profile and morphology as they transition from spermatogonial stem cells through to mature spermatozoa is dependent upon their association with Sertoli cells. Sertoli cells are crucial for survival and maturation of male germ cells. Two recent papers, Holembowski et al. [1] and Inoue et al. [2] have described a surprising role for the p53 family member, p73, in regulation of germ cell-Sertoli cell adhesion.http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=6;spage=799;epage=800;aulast=Abud |
| spellingShingle | Helen E Abud Gary R Hime Regulation of cell adhesion in the testis: a new role for p73 Asian Journal of Andrology |
| title | Regulation of cell adhesion in the testis: a new role for p73 |
| title_full | Regulation of cell adhesion in the testis: a new role for p73 |
| title_fullStr | Regulation of cell adhesion in the testis: a new role for p73 |
| title_full_unstemmed | Regulation of cell adhesion in the testis: a new role for p73 |
| title_short | Regulation of cell adhesion in the testis: a new role for p73 |
| title_sort | regulation of cell adhesion in the testis a new role for p73 |
| url | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=6;spage=799;epage=800;aulast=Abud |
| work_keys_str_mv | AT heleneabud regulationofcelladhesioninthetestisanewroleforp73 AT garyrhime regulationofcelladhesioninthetestisanewroleforp73 |