Neurologic Complications of Influenza B Virus Infection in Adults, Romania
We characterized influenza B virus–related neurologic manifestations in an unusually high number of hospitalized adults at a tertiary care facility in Romania during the 2014–15 influenza epidemic season. Of 32 patients with a confirmed laboratory diagnosis of influenza B virus infection, neurologic...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2017-04-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/23/4/16-1317_article |
| _version_ | 1828789278504648704 |
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| author | Corneliu P. Popescu Simin A. Florescu Emilia Lupulescu Mihaela Zaharia Gratiela Tardei Mihaela Lazar Emanoil Ceausu Simona M. Ruta |
| author_facet | Corneliu P. Popescu Simin A. Florescu Emilia Lupulescu Mihaela Zaharia Gratiela Tardei Mihaela Lazar Emanoil Ceausu Simona M. Ruta |
| author_sort | Corneliu P. Popescu |
| collection | DOAJ |
| description | We characterized influenza B virus–related neurologic manifestations in an unusually high number of hospitalized adults at a tertiary care facility in Romania during the 2014–15 influenza epidemic season. Of 32 patients with a confirmed laboratory diagnosis of influenza B virus infection, neurologic complications developed in 7 adults (median age 31 years). These complications were clinically diagnosed as confirmed encephalitis (4 patients), possible encephalitis (2 patients), and cerebellar ataxia (1 patient). Two of the patients died. Virus sequencing identified influenza virus B (Yam)-lineage clade 3, which is representative of the B/Phuket/3073/2013 strain, in 4 patients. None of the patients had been vaccinated against influenza. These results suggest that influenza B virus can cause a severe clinical course and should be considered as an etiologic factor for encephalitis. |
| first_indexed | 2024-12-12T01:09:40Z |
| format | Article |
| id | doaj.art-f8090d48f7614da4bc66deac0b3e482c |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-12T01:09:40Z |
| publishDate | 2017-04-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-f8090d48f7614da4bc66deac0b3e482c2022-12-22T00:43:31ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592017-04-0123457458110.3201/eid2304.161317Neurologic Complications of Influenza B Virus Infection in Adults, RomaniaCorneliu P. PopescuSimin A. FlorescuEmilia LupulescuMihaela ZahariaGratiela TardeiMihaela LazarEmanoil CeausuSimona M. RutaWe characterized influenza B virus–related neurologic manifestations in an unusually high number of hospitalized adults at a tertiary care facility in Romania during the 2014–15 influenza epidemic season. Of 32 patients with a confirmed laboratory diagnosis of influenza B virus infection, neurologic complications developed in 7 adults (median age 31 years). These complications were clinically diagnosed as confirmed encephalitis (4 patients), possible encephalitis (2 patients), and cerebellar ataxia (1 patient). Two of the patients died. Virus sequencing identified influenza virus B (Yam)-lineage clade 3, which is representative of the B/Phuket/3073/2013 strain, in 4 patients. None of the patients had been vaccinated against influenza. These results suggest that influenza B virus can cause a severe clinical course and should be considered as an etiologic factor for encephalitis.https://wwwnc.cdc.gov/eid/article/23/4/16-1317_articleinfluenza B virusvirusesinfluenzainfluenza vaccineneurologic complicationsmeningitis/encephalitis |
| spellingShingle | Corneliu P. Popescu Simin A. Florescu Emilia Lupulescu Mihaela Zaharia Gratiela Tardei Mihaela Lazar Emanoil Ceausu Simona M. Ruta Neurologic Complications of Influenza B Virus Infection in Adults, Romania Emerging Infectious Diseases influenza B virus viruses influenza influenza vaccine neurologic complications meningitis/encephalitis |
| title | Neurologic Complications of Influenza B Virus Infection in Adults, Romania |
| title_full | Neurologic Complications of Influenza B Virus Infection in Adults, Romania |
| title_fullStr | Neurologic Complications of Influenza B Virus Infection in Adults, Romania |
| title_full_unstemmed | Neurologic Complications of Influenza B Virus Infection in Adults, Romania |
| title_short | Neurologic Complications of Influenza B Virus Infection in Adults, Romania |
| title_sort | neurologic complications of influenza b virus infection in adults romania |
| topic | influenza B virus viruses influenza influenza vaccine neurologic complications meningitis/encephalitis |
| url | https://wwwnc.cdc.gov/eid/article/23/4/16-1317_article |
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