Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring

Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring

Arylpiperazines represent one of the most important classes of 5-HT<sub>1A</sub>R ligands and have attracted considerable interests for their versatile properties in chemistry and pharmacology, leading to the research of new derivatives that has been focused on the modification of one or...

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Bibliographic Details
Main Authors: Giorgia Andreozzi, Maria Rosaria Ambrosio, Elisa Magli, Giovanni Maneli, Beatrice Severino, Angela Corvino, Rosa Sparaco, Elisa Perissutti, Francesco Frecentese, Vincenzo Santagada, Anna Leśniak, Magdalena Bujalska-Zadrożny, Giuseppe Caliendo, Pietro Formisano, Ferdinando Fiorino
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Pharmaceuticals
Subjects:
arylpiperazines
5-HT<sub>1A</sub> ligands
binding assays, in vitro assay, cytotoxic activity
Online Access:https://www.mdpi.com/1424-8247/16/10/1483

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https://www.mdpi.com/1424-8247/16/10/1483

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