Suckling by Schistosoma mansoni-infected mothers restored IgG2a and TGF-β production, but not IL-6 and delayed-type hypersensitivity in IL-12/IL-23-deficient mice

Suckling by Schistosoma mansoni-infected mothers restored IgG2a and TGF-β production, but not IL-6 and delayed-type hypersensitivity in IL-12/IL-23-deficient mice

Abstract INTRODUCTION Suckling by schistosomotic mice improves anti-ovalbumin (OA) antibody production, while delayed-type hypersensitivity (DTH) remains unaffected. This property of milk from schistosomotic mice was investigated in IL-12/IL-23-deficient mice (IL-12p40KO). METHODS We compared an...

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Bibliographic Details
Main Authors: Fabiana Leticia da Silva, Maria da Conceição Silva, Gabriela Calixto Ribeiro de Holanda, Eridan de Medeiros Coutinho, Silvia Maria Lucena Montenegro, Clarice Neuenschwander Lins de Morais, Valdênia Maria Oliveira de Souza
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2021-03-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Schistosomiasis mansoni
Suckling
Hypersensitivity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822021000100636&tlng=en

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