Methodological Research on Image Registration Based on Human Brain Tissue In Vivo

As one of the critical steps in brain imaging analysis and processing, brain image registration plays a significant role. In this paper, we proposed a technique of human brain image registration based on tissue morphology in vivo to address the problems of previous image registration. First, differe...

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Main Authors: Jiaofen Nan, Junya Su, Jincan Zhang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Electronics
Subjects:
Online Access:https://www.mdpi.com/2079-9292/12/3/738
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author Jiaofen Nan
Junya Su
Jincan Zhang
author_facet Jiaofen Nan
Junya Su
Jincan Zhang
author_sort Jiaofen Nan
collection DOAJ
description As one of the critical steps in brain imaging analysis and processing, brain image registration plays a significant role. In this paper, we proposed a technique of human brain image registration based on tissue morphology in vivo to address the problems of previous image registration. First, different feature points were extracted and combined, including those at the boundary of different brain tissues and those of the maximum or minimum from the original image. Second, feature points were screened through eliminating their wrong matching pairs between moving image and reference image. Finally, the remaining matching pairs of feature points were used to generate the model parameters of spatial transformation, with which the brain image registration can be finished by combining interpolation techniques. Results showed that compared with the Surf, Demons, and Sift algorithms, the proposed method can perform better not only for four quantitative indicators (mean square differences, normalized cross correlation, normalized mutual information and mutual information) but also in spatial location, size, appearance contour, and registration details. The findings may suggest that the proposed method will be of great value for brain image reconstruction, fusion, and statistical comparison analysis.
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spelling doaj.art-f80f0ef59510428fa60232601282a09b2023-11-16T16:30:46ZengMDPI AGElectronics2079-92922023-02-0112373810.3390/electronics12030738Methodological Research on Image Registration Based on Human Brain Tissue In VivoJiaofen Nan0Junya Su1Jincan Zhang2School of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou 450001, ChinaSchool of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou 450001, ChinaSchool of Management Engineering, Zhengzhou University, Zhengzhou 450001, ChinaAs one of the critical steps in brain imaging analysis and processing, brain image registration plays a significant role. In this paper, we proposed a technique of human brain image registration based on tissue morphology in vivo to address the problems of previous image registration. First, different feature points were extracted and combined, including those at the boundary of different brain tissues and those of the maximum or minimum from the original image. Second, feature points were screened through eliminating their wrong matching pairs between moving image and reference image. Finally, the remaining matching pairs of feature points were used to generate the model parameters of spatial transformation, with which the brain image registration can be finished by combining interpolation techniques. Results showed that compared with the Surf, Demons, and Sift algorithms, the proposed method can perform better not only for four quantitative indicators (mean square differences, normalized cross correlation, normalized mutual information and mutual information) but also in spatial location, size, appearance contour, and registration details. The findings may suggest that the proposed method will be of great value for brain image reconstruction, fusion, and statistical comparison analysis.https://www.mdpi.com/2079-9292/12/3/738brain tissue segmentationfeature selectionhuman brainimage registration
spellingShingle Jiaofen Nan
Junya Su
Jincan Zhang
Methodological Research on Image Registration Based on Human Brain Tissue In Vivo
Electronics
brain tissue segmentation
feature selection
human brain
image registration
title Methodological Research on Image Registration Based on Human Brain Tissue In Vivo
title_full Methodological Research on Image Registration Based on Human Brain Tissue In Vivo
title_fullStr Methodological Research on Image Registration Based on Human Brain Tissue In Vivo
title_full_unstemmed Methodological Research on Image Registration Based on Human Brain Tissue In Vivo
title_short Methodological Research on Image Registration Based on Human Brain Tissue In Vivo
title_sort methodological research on image registration based on human brain tissue in vivo
topic brain tissue segmentation
feature selection
human brain
image registration
url https://www.mdpi.com/2079-9292/12/3/738
work_keys_str_mv AT jiaofennan methodologicalresearchonimageregistrationbasedonhumanbraintissueinvivo
AT junyasu methodologicalresearchonimageregistrationbasedonhumanbraintissueinvivo
AT jincanzhang methodologicalresearchonimageregistrationbasedonhumanbraintissueinvivo