Evaluating [68Ga]Ga-p14-032 as a Novel PET Tracer for Diagnosis Cerebral Amyloid Angiopathy

Evaluating [68Ga]Ga-p14-032 as a Novel PET Tracer for Diagnosis Cerebral Amyloid Angiopathy

Objective: We aimed to investigate the distribution of [68Ga]Ga-p14-032, a novel PET ligand that binds to vascular amyloid, in patients diagnosed clinically with probable cerebral amyloid angiopathy (CAA) compared with patients with Alzheimer's disease (AD) and normal controls (NC).Methods: Thi...

Full description

Bibliographic Details
Main Authors:	Qihui Zhang, Xiaobin Zhao, Peng Lei, Hank F. Kung, Zhi Yang, Lin Zhu, Shujing Wang, Hua Zhu, Xiangxi Meng, Yunyun Duan, Li Sun, Jianwei Pan, Ruixue Ma, Haiyan Hong, Xingquan Zhao, Andrew Demchuk, Eric E. Smith, Yongjun Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-10-01
Series:	Frontiers in Neurology
Subjects:	cerebral amyloid angiopathy amyloid-β PET tracer Alzheimer's disease PET/MRI
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2021.702185/full

Similar Items

Cerebral amyloid angiopathy distribution in older people: A cautionary note
by: Vafa Alakbarzade, et al.
Published: (2021-01-01)

Cerebral Amyloid Angiopathy with Lobar Haemorrhages and CAA-Related Inflammation in an Indian Family
by: Boby Varkey Maramattom
Published: (2022-01-01)

Amyloid and tau PET in cerebral amyloid angiopathy-related inflammation two case reports and literature review
by: Jhih-Yong Yang, et al.
Published: (2023-04-01)

Cerebral Microbleeds
by: Çağla
Published: (2019-12-01)

Cerebral Amyloid Angiopathy: An Undeniable Small Vessel Disease
by: Litao Wang, et al.
Published: (2024-01-01)

Fluid biomarkers in cerebral amyloid angiopathy
by: Seyed Mehrdad Savar, et al.
Published: (2024-01-01)

Cerebral amyloid angiopathy-related inflammation (CAARI): case report
by: Karol Adam Makarewicz, et al.
Published: (2019-06-01)

Undiagnosed senile systemic amyloidosis with mesenteric angiopathy leading to fatal outcomes: Two case series with a review of literature
by: Avneesh Gupta, et al.
Published: (2017-01-01)

Cerebral Amyloid Angiopathy-Related Inflammation following Multiple Cancers and Chemotherapies
by: Christophe Severijns, et al.
Published: (2022-03-01)

Cerebral amyloid angiopathy-related inflammation presenting with a stroke-like episode
by: Ana Rita Gaspar, et al.
Published: (2023-02-01)

Resorufin analogs preferentially bind cerebrovascular amyloid: potential use as imaging ligands for cerebral amyloid angiopathy
by: Han Byung, et al.
Published: (2011-12-01)

Cerebral amyloid angiopathy
by: Dan Popescu, et al.
Published: (2010-06-01)

Synthesis, radiolabeling, and evaluation of 68Ga-labeled aminoquinoxaline derivative as a potent PFKFB3-targeted PET tracer
by: Feng Chen, et al.
Published: (2023-03-01)

Callistephin inhibits amyloid-β protein aggregation and determined cytotoxicity against cerebrovascular smooth muscle cells as an in vitro model of cerebral amyloid angiopathy
by: E. Ruifang, et al.
Published: (2022-02-01)

Histological and immunohistochemical characteristics of cerebral amyloid angiopathy in elderly dogs
by: Slađan Nešić, et al.
Published: (2017-01-01)

Case report of iatrogenic cerebral amyloid angiopathy after exposure to Lyodura: an Australian perspective
by: Claire Muller, et al.
Published: (2023-05-01)

White matter hyper-intensity patters in patients with amyloid angiopathy and cerebellum involvement
by: Pavel Gavriliuc, et al.
Published: (2020-09-01)

Cerebral amyloid angiopathy: A clinicopathological study of three cases
by: Panicker Jalesh, et al.
Published: (2010-01-01)

Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy
by: Monica Xiong, et al.
Published: (2023-03-01)

Progress in the study of the correlation between cerebral amyloid angiopathy and Alzheimer's disease
by: LU Zheng⁃qi, et al.
Published: (2021-10-01)

Advances of cerebral amyloid angiopathy and related cognitive impairment
by: Zhen ZHEN, et al.
Published: (2019-08-01)

The association between hypertensive angiopathy and cerebral amyloid angiopathy in primary intracerebral hemorrhage
by: Yuyi Zhu, et al.
Published: (2023-10-01)

Intracerebral Hemorrhage Recurrence in Patients with and without Cerebral Amyloid Angiopathy
by: João Pinho, et al.
Published: (2021-01-01)

The role of amyloid beta clearance in cerebral amyloid angiopathy: more potential therapeutic targets
by: Xue-mei Qi, et al.
Published: (2017-08-01)

Analysis on two cases of cerebral amyloid angiopathy-related inflammation
by: Dong-yang HU, et al.
Published: (2019-01-01)

Cerebral amyloid angiopathy (case report)
by: L. A. Dobrynina, et al.
Published: (2017-02-01)

Main features of hereditary cerebral amyloid angiopathies: A systematic review
by: Alessandro Biffi
Published: (2022-01-01)

A Case of Possible Cerebral Amyloid Angiopathy Presenting with Diffuse Cerebellar Hemosiderosis
by: Selen Gür Özmen, et al.
Published: (2013-09-01)

Understanding the Pathophysiology of Cerebral Amyloid Angiopathy
by: Laura Gatti, et al.
Published: (2020-05-01)

Dissecting the Crosstalk between Endothelial Mitochondrial Damage, Vascular Inflammation, and Neurodegeneration in Cerebral Amyloid Angiopathy and Alzheimer’s Disease
by: Rebecca M. Parodi-Rullán, et al.
Published: (2021-10-01)

Gait in Cerebral Amyloid Angiopathy
by: Breni Sharma, et al.
Published: (2022-10-01)

Cerebral Amyloid Angiopathy: A Case Report and Literature ...
by: Orkide Kutlu, et al.
Published: (2015-03-01)

Early stage of cerebral amyloid angiopathy revealed by follow-up of a minimal head injury
by: Fallou Galass Niang, MD, et al.
Published: (2023-12-01)

Recurrent Subarachnoid Bleeding and Superficial Siderosis in a Patient with Histopathologically Proven Cerebral Amyloid Angiopathy
by: P. Profice, et al.
Published: (2011-05-01)

Multiple Approaches to Diffusion Magnetic Resonance Imaging in Hereditary Cerebral Amyloid Angiopathy Mutation Carriers
by: Tijn M. Schouten, et al.
Published: (2019-02-01)

Rare forms of cerebral amyloid angiopathy: pathogenesis, biological and clinical features of CAA-ri and iCAA
by: Benedetta Storti, et al.
Published: (2023-07-01)

Cerebral Amyloid Angiopathy Presenting with Synchronous Bilateral Intracerebral Macrohemorrhages
by: Jeremy S. Shelton, et al.
Published: (2015-11-01)

Association of antithrombotic therapy with postoperative rebleeding in patients with cerebral amyloid angiopathy
by: Taro Yanagawa, et al.
Published: (2023-05-01)

Non-inflammatory cerebral amyloid angiopathy as a cause of rapidly progressive dementia: A case study
by: Leonel Tadao Takada, et al.

Cerebrospinal fluid levels of the neurotrophic factor neuroleukin are increased in early Alzheimer’s disease, but not in cerebral amyloid angiopathy
by: Anna M. De Kort, et al.
Published: (2021-09-01)