Glial cell induced neural differentiation of bone marrow stromal cells
Bone marrow stromal cells (BMSCs) have an important application prospect in the field of cell therapy for various neurodegenerative diseases, and inducing factors that regulate BMSC differentiation are proposed as a promising therapeutic strategy. In this study, we explored the effect of glial cell-...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2020-09-01
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| Series: | Open Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/med-2020-0229 |
| _version_ | 1818356061565878272 |
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| author | Ma Qiang Cai Ming Shang Jing-Wei Yang Jun Gu Xin-Yi Liu Wen-Bo Yang Qing |
| author_facet | Ma Qiang Cai Ming Shang Jing-Wei Yang Jun Gu Xin-Yi Liu Wen-Bo Yang Qing |
| author_sort | Ma Qiang |
| collection | DOAJ |
| description | Bone marrow stromal cells (BMSCs) have an important application prospect in the field of cell therapy for various neurodegenerative diseases, and inducing factors that regulate BMSC differentiation are proposed as a promising therapeutic strategy. In this study, we explored the effect of glial cell-derived neurotrophic factor (GDNF) on the course of BMSC differentiation. |
| first_indexed | 2024-12-13T19:51:13Z |
| format | Article |
| id | doaj.art-f819fc2e817045648d4c190efd660a9b |
| institution | Directory Open Access Journal |
| issn | 2391-5463 |
| language | English |
| last_indexed | 2024-12-13T19:51:13Z |
| publishDate | 2020-09-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj.art-f819fc2e817045648d4c190efd660a9b2022-12-21T23:33:26ZengDe GruyterOpen Medicine2391-54632020-09-0115195496110.1515/med-2020-0229med-2020-0229Glial cell induced neural differentiation of bone marrow stromal cellsMa Qiang0Cai Ming1Shang Jing-Wei2Yang Jun3Gu Xin-Yi4Liu Wen-Bo5Yang Qing6School of Life Science and Biotechnology, Dalian University of Technology, No. 2 Linggong Road, Dalian 116023, Liaoning Province, ChinaDepartment of Neurology, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, Liaoning Province, ChinaDepartment of Neurology, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, Liaoning Province, ChinaSchool of Life Science and Biotechnology, Dalian University of Technology, No. 2 Linggong Road, Dalian 116023, Liaoning Province, ChinaDepartment of Neurology, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, Liaoning Province, ChinaDepartment of Neurology, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, Liaoning Province, ChinaSchool of Life Science and Biotechnology, Dalian University of Technology, No. 2 Linggong Road, Dalian 116023, Liaoning Province, ChinaBone marrow stromal cells (BMSCs) have an important application prospect in the field of cell therapy for various neurodegenerative diseases, and inducing factors that regulate BMSC differentiation are proposed as a promising therapeutic strategy. In this study, we explored the effect of glial cell-derived neurotrophic factor (GDNF) on the course of BMSC differentiation.https://doi.org/10.1515/med-2020-0229alzheimer’s diseasebone marrow stromal cellscell therapyglial cell-derived neurotrophic factorneuronal differentiation |
| spellingShingle | Ma Qiang Cai Ming Shang Jing-Wei Yang Jun Gu Xin-Yi Liu Wen-Bo Yang Qing Glial cell induced neural differentiation of bone marrow stromal cells Open Medicine alzheimer’s disease bone marrow stromal cells cell therapy glial cell-derived neurotrophic factor neuronal differentiation |
| title | Glial cell induced neural differentiation of bone marrow stromal cells |
| title_full | Glial cell induced neural differentiation of bone marrow stromal cells |
| title_fullStr | Glial cell induced neural differentiation of bone marrow stromal cells |
| title_full_unstemmed | Glial cell induced neural differentiation of bone marrow stromal cells |
| title_short | Glial cell induced neural differentiation of bone marrow stromal cells |
| title_sort | glial cell induced neural differentiation of bone marrow stromal cells |
| topic | alzheimer’s disease bone marrow stromal cells cell therapy glial cell-derived neurotrophic factor neuronal differentiation |
| url | https://doi.org/10.1515/med-2020-0229 |
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