Gastrosplenic fistula due to splenic lymphoma: two case reports and review of the literature
Abstract Background Gastrosplenic fistula is a rare and potentially fatal complication of various conditions. Lymphoma is the most common cause. It can occur spontaneously or after chemotherapy. Gastrosplenic fistula diagnosis can be confused with a splenic abscess because of the presence of air int...
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | Journal of Medical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13256-024-04441-2 |
| _version_ | 1797266810628734976 |
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| author | Feryel Letaief Ksontini Yosra Zaimi Isaad Nefzi Salim Khrouf Myriam Ayari Sonia Sghaier Asma Zidi Houcine Magherbi Mouna Ayadi |
| author_facet | Feryel Letaief Ksontini Yosra Zaimi Isaad Nefzi Salim Khrouf Myriam Ayari Sonia Sghaier Asma Zidi Houcine Magherbi Mouna Ayadi |
| author_sort | Feryel Letaief Ksontini |
| collection | DOAJ |
| description | Abstract Background Gastrosplenic fistula is a rare and potentially fatal complication of various conditions. Lymphoma is the most common cause. It can occur spontaneously or after chemotherapy. Gastrosplenic fistula diagnosis can be confused with a splenic abscess because of the presence of air into the mass. The computed tomography identification of the fistulous tract is the key to a right diagnosis. Treatment modalities include surgical resection, chemotherapy, or a combination of both. Case presentation Here we report two patients with gastrosplenic fistula due to diffuse large B cell lymphoma. The first patient was a 54-year-old Caucasian woman with an enormous primary splenic diffuse large B cell lymphoma leading to the development of a spontaneous fistula in the stomach. The second patient was a 48-year-old Caucasian male patient with an enormous splenic diffuse large B cell lymphoma complicated by fistula after chemotherapy. Both patients died of septic shock several days after surgery. Conclusion Gastrosplenic fistula is a rare complication with a poor-prognosis, for which surgery is currently the preferred treatment. |
| first_indexed | 2024-04-25T01:06:37Z |
| format | Article |
| id | doaj.art-f81b7c00da1c424f814eec08cf88381e |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-04-25T01:06:37Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-f81b7c00da1c424f814eec08cf88381e2024-03-10T12:13:59ZengBMCJournal of Medical Case Reports1752-19472024-03-011811410.1186/s13256-024-04441-2Gastrosplenic fistula due to splenic lymphoma: two case reports and review of the literatureFeryel Letaief Ksontini0Yosra Zaimi1Isaad Nefzi2Salim Khrouf3Myriam Ayari4Sonia Sghaier5Asma Zidi6Houcine Magherbi7Mouna Ayadi8Department of Medical Oncology, Salah Azaiez Institute, Tunis El Manar UniversityDepartment of Gastroenterology, Charles Nicolle Hospital, Tunis El Manar UniversityDepartment of Medical Oncology, Salah Azaiez Institute, Tunis El Manar UniversityDepartment of Medical Oncology, Salah Azaiez Institute, Tunis El Manar UniversityDepartment of Gastroenterology, Charles Nicolle Hospital, Tunis El Manar UniversityDepartment of Surgery A, La Rabta Hospital, Tunis El Manar UniversityDepartment of Surgery A, La Rabta Hospital, Tunis El Manar UniversityDepartment of Radiology, Salah Azaiez Institute, Tunis El Manar UniversityDepartment of Medical Oncology, Salah Azaiez Institute, Tunis El Manar UniversityAbstract Background Gastrosplenic fistula is a rare and potentially fatal complication of various conditions. Lymphoma is the most common cause. It can occur spontaneously or after chemotherapy. Gastrosplenic fistula diagnosis can be confused with a splenic abscess because of the presence of air into the mass. The computed tomography identification of the fistulous tract is the key to a right diagnosis. Treatment modalities include surgical resection, chemotherapy, or a combination of both. Case presentation Here we report two patients with gastrosplenic fistula due to diffuse large B cell lymphoma. The first patient was a 54-year-old Caucasian woman with an enormous primary splenic diffuse large B cell lymphoma leading to the development of a spontaneous fistula in the stomach. The second patient was a 48-year-old Caucasian male patient with an enormous splenic diffuse large B cell lymphoma complicated by fistula after chemotherapy. Both patients died of septic shock several days after surgery. Conclusion Gastrosplenic fistula is a rare complication with a poor-prognosis, for which surgery is currently the preferred treatment.https://doi.org/10.1186/s13256-024-04441-2LymphomaGastrosplenic fistulaChemotherapySurgery |
| spellingShingle | Feryel Letaief Ksontini Yosra Zaimi Isaad Nefzi Salim Khrouf Myriam Ayari Sonia Sghaier Asma Zidi Houcine Magherbi Mouna Ayadi Gastrosplenic fistula due to splenic lymphoma: two case reports and review of the literature Journal of Medical Case Reports Lymphoma Gastrosplenic fistula Chemotherapy Surgery |
| title | Gastrosplenic fistula due to splenic lymphoma: two case reports and review of the literature |
| title_full | Gastrosplenic fistula due to splenic lymphoma: two case reports and review of the literature |
| title_fullStr | Gastrosplenic fistula due to splenic lymphoma: two case reports and review of the literature |
| title_full_unstemmed | Gastrosplenic fistula due to splenic lymphoma: two case reports and review of the literature |
| title_short | Gastrosplenic fistula due to splenic lymphoma: two case reports and review of the literature |
| title_sort | gastrosplenic fistula due to splenic lymphoma two case reports and review of the literature |
| topic | Lymphoma Gastrosplenic fistula Chemotherapy Surgery |
| url | https://doi.org/10.1186/s13256-024-04441-2 |
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