COVID-19 with extreme thrombocytosis: a case report and its possible mechanisms
Background: Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has spread globally becoming a pandemic. The clinical manifestations of COVID-19 vary from asymptomatic to symptomatic disease. Hematologic manifestation which is commonly found in...
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2022-01-01
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| Series: | Caspian Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://caspjim.com/article-1-3103-en.html |
| _version_ | 1811272539427569664 |
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| author | Cathleen Kenya Nur Chandra Bunawan Hardijatmo Muljo Nugroho Annisa Dian Harlivasari Edgar David Sigarlaki Ikhwan Rinaldi |
| author_facet | Cathleen Kenya Nur Chandra Bunawan Hardijatmo Muljo Nugroho Annisa Dian Harlivasari Edgar David Sigarlaki Ikhwan Rinaldi |
| author_sort | Cathleen Kenya |
| collection | DOAJ |
| description | Background: Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has spread globally becoming a pandemic. The clinical manifestations of COVID-19 vary from asymptomatic to symptomatic disease. Hematologic manifestation which is commonly found in COVID-19 patients is thrombocytopenia whereas thrombocytosis is rarely reported.
Case Presentation: We report a case of a 55-year-old woman with one week history of fever which spike along the day, dry cough, anosmia, nausea, epigastric pain and loss of appetite. She lived in local transmission area. The patient was diagnosed as mild suspected COVID-19 and confirmed with nasopharyngeal and oropharyngeal swab test (positive result). On admission, the number of platelet count was within normal limit but progressively increased exceeding 1000 x109/L accompanied by worsening of the clinical condition. Interestingly, to our knowledge, no such case has ever been reported. In this study, we will discuss the possible mechanisms of its changes.
Conclusions: COVID-19 can present with extreme thrombocytosis. Thus, monitoring the platelet count during hospitalization can be helpful for anticipating worsening conditions and progression of COVID-19. |
| first_indexed | 2024-04-12T22:42:08Z |
| format | Article |
| id | doaj.art-f81db7d877d544a0a366f59f33ea3d93 |
| institution | Directory Open Access Journal |
| issn | 2008-6164 2008-6172 |
| language | English |
| last_indexed | 2024-04-12T22:42:08Z |
| publishDate | 2022-01-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Internal Medicine |
| spelling | doaj.art-f81db7d877d544a0a366f59f33ea3d932022-12-22T03:13:42ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722022-01-0113Covid 19 Supplement 2289294COVID-19 with extreme thrombocytosis: a case report and its possible mechanismsCathleen Kenya0Nur Chandra Bunawan1Hardijatmo Muljo Nugroho2Annisa Dian Harlivasari3Edgar David Sigarlaki4Ikhwan Rinaldi5 Regional Public Hospital of Kramat Jati, Jakarta, Indonesia COVID-19 Task Force in Regional Public Hospital of Kramat Jati, Jakarta, Indonesia COVID-19 Task Force in Regional Public Hospital of Kramat Jati, Jakarta, Indonesia COVID-19 Task Force in Regional Public Hospital of Kramat Jati, Jakarta, Indonesia Regional Public Hospital of Kramat Jati, Jakarta, Indonesia Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia Background: Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has spread globally becoming a pandemic. The clinical manifestations of COVID-19 vary from asymptomatic to symptomatic disease. Hematologic manifestation which is commonly found in COVID-19 patients is thrombocytopenia whereas thrombocytosis is rarely reported. Case Presentation: We report a case of a 55-year-old woman with one week history of fever which spike along the day, dry cough, anosmia, nausea, epigastric pain and loss of appetite. She lived in local transmission area. The patient was diagnosed as mild suspected COVID-19 and confirmed with nasopharyngeal and oropharyngeal swab test (positive result). On admission, the number of platelet count was within normal limit but progressively increased exceeding 1000 x109/L accompanied by worsening of the clinical condition. Interestingly, to our knowledge, no such case has ever been reported. In this study, we will discuss the possible mechanisms of its changes. Conclusions: COVID-19 can present with extreme thrombocytosis. Thus, monitoring the platelet count during hospitalization can be helpful for anticipating worsening conditions and progression of COVID-19.http://caspjim.com/article-1-3103-en.htmlcovid-19sars-cov-2hematologic manifestationsthrombocytosisplatelet count |
| spellingShingle | Cathleen Kenya Nur Chandra Bunawan Hardijatmo Muljo Nugroho Annisa Dian Harlivasari Edgar David Sigarlaki Ikhwan Rinaldi COVID-19 with extreme thrombocytosis: a case report and its possible mechanisms Caspian Journal of Internal Medicine covid-19 sars-cov-2 hematologic manifestations thrombocytosis platelet count |
| title | COVID-19 with extreme thrombocytosis: a case report and its possible mechanisms |
| title_full | COVID-19 with extreme thrombocytosis: a case report and its possible mechanisms |
| title_fullStr | COVID-19 with extreme thrombocytosis: a case report and its possible mechanisms |
| title_full_unstemmed | COVID-19 with extreme thrombocytosis: a case report and its possible mechanisms |
| title_short | COVID-19 with extreme thrombocytosis: a case report and its possible mechanisms |
| title_sort | covid 19 with extreme thrombocytosis a case report and its possible mechanisms |
| topic | covid-19 sars-cov-2 hematologic manifestations thrombocytosis platelet count |
| url | http://caspjim.com/article-1-3103-en.html |
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