Long-term outcomes of total ureterectomy with ileal-ureteral substitution treatment for ureteral cancer: a single-center experience
Abstract Background To explore the feasibility and long-term outcomes of renal preservation in a retrospective cohort of patients with ureteral urothelial carcinoma undergoing total ureterectomy with ileal-ureteral substitution. Methods A retrospective review of the data from patients treated with t...
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| Format: | Article |
| Language: | English |
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BMC
2018-08-01
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| Series: | BMC Urology |
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| Online Access: | http://link.springer.com/article/10.1186/s12894-018-0389-5 |
| _version_ | 1818480137034792960 |
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| author | Yin-Chien Ou Che-Yuan Hu Hong-Lin Cheng Wen-Horng Yang |
| author_facet | Yin-Chien Ou Che-Yuan Hu Hong-Lin Cheng Wen-Horng Yang |
| author_sort | Yin-Chien Ou |
| collection | DOAJ |
| description | Abstract Background To explore the feasibility and long-term outcomes of renal preservation in a retrospective cohort of patients with ureteral urothelial carcinoma undergoing total ureterectomy with ileal-ureteral substitution. Methods A retrospective review of the data from patients treated with total ureterectomy with ileal-ureteral substitution from 1988 to 2016 was performed. The pre-operative oncological status, long-term oncological outcome, long-term renal functional outcome, early and late complications were analyzed. Results A total of eight patients with a median age of 70 years were included. The median follow-up time was 109 months. Six patients had multi-focal tumor involvement over the target ureter, and six patients had bilateral upper tract involvement. Only one patient encountered the upper-tract recurrence. The 2 and 5-year cancer-specific survival rates were 87.5 and 75.0%, respectively. The renal function was well-preserved in most patients, with only one patient needed life-long postoperative hemodialysis. Five patients experienced early complications and four patients experienced late complications. No perioperative mortality happened. Conclusions A total ureterectomy with an ileal-ureteral substitution is feasible for treating ureteral urothelial carcinoma when a renal-sparing procedure is indicated. It provides good long-term oncological outcomes over the upper tract, and it also preserves the renal function. |
| first_indexed | 2024-12-10T11:19:13Z |
| format | Article |
| id | doaj.art-f81dda90417745d9b05f475eaa11773a |
| institution | Directory Open Access Journal |
| issn | 1471-2490 |
| language | English |
| last_indexed | 2024-12-10T11:19:13Z |
| publishDate | 2018-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Urology |
| spelling | doaj.art-f81dda90417745d9b05f475eaa11773a2022-12-22T01:51:02ZengBMCBMC Urology1471-24902018-08-011811710.1186/s12894-018-0389-5Long-term outcomes of total ureterectomy with ileal-ureteral substitution treatment for ureteral cancer: a single-center experienceYin-Chien Ou0Che-Yuan Hu1Hong-Lin Cheng2Wen-Horng Yang3Department of Urology, National Cheng Kung University HospitalDepartment of Urology, National Cheng Kung University HospitalDepartment of Urology, National Cheng Kung University HospitalDepartment of Urology, National Cheng Kung University HospitalAbstract Background To explore the feasibility and long-term outcomes of renal preservation in a retrospective cohort of patients with ureteral urothelial carcinoma undergoing total ureterectomy with ileal-ureteral substitution. Methods A retrospective review of the data from patients treated with total ureterectomy with ileal-ureteral substitution from 1988 to 2016 was performed. The pre-operative oncological status, long-term oncological outcome, long-term renal functional outcome, early and late complications were analyzed. Results A total of eight patients with a median age of 70 years were included. The median follow-up time was 109 months. Six patients had multi-focal tumor involvement over the target ureter, and six patients had bilateral upper tract involvement. Only one patient encountered the upper-tract recurrence. The 2 and 5-year cancer-specific survival rates were 87.5 and 75.0%, respectively. The renal function was well-preserved in most patients, with only one patient needed life-long postoperative hemodialysis. Five patients experienced early complications and four patients experienced late complications. No perioperative mortality happened. Conclusions A total ureterectomy with an ileal-ureteral substitution is feasible for treating ureteral urothelial carcinoma when a renal-sparing procedure is indicated. It provides good long-term oncological outcomes over the upper tract, and it also preserves the renal function.http://link.springer.com/article/10.1186/s12894-018-0389-5Upper urinary tract urothelial carcinomaTotal ureterectomyIleumReconstructive surgical procedures |
| spellingShingle | Yin-Chien Ou Che-Yuan Hu Hong-Lin Cheng Wen-Horng Yang Long-term outcomes of total ureterectomy with ileal-ureteral substitution treatment for ureteral cancer: a single-center experience BMC Urology Upper urinary tract urothelial carcinoma Total ureterectomy Ileum Reconstructive surgical procedures |
| title | Long-term outcomes of total ureterectomy with ileal-ureteral substitution treatment for ureteral cancer: a single-center experience |
| title_full | Long-term outcomes of total ureterectomy with ileal-ureteral substitution treatment for ureteral cancer: a single-center experience |
| title_fullStr | Long-term outcomes of total ureterectomy with ileal-ureteral substitution treatment for ureteral cancer: a single-center experience |
| title_full_unstemmed | Long-term outcomes of total ureterectomy with ileal-ureteral substitution treatment for ureteral cancer: a single-center experience |
| title_short | Long-term outcomes of total ureterectomy with ileal-ureteral substitution treatment for ureteral cancer: a single-center experience |
| title_sort | long term outcomes of total ureterectomy with ileal ureteral substitution treatment for ureteral cancer a single center experience |
| topic | Upper urinary tract urothelial carcinoma Total ureterectomy Ileum Reconstructive surgical procedures |
| url | http://link.springer.com/article/10.1186/s12894-018-0389-5 |
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