Helicobacter pylori Infection in Geriatric Patients: Current Situation and Treatment Regimens
Helicobacter pylori (H. pylori) has so far infected more than half the global population. It is the most important and controllable risk factor for gastric cancer. The elderly, who are at a higher incidence of the infection, are also commonly found to develop antibiotic resistance. The symptoms, dia...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-09-01
|
Series: | Frontiers in Medicine |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2021.713908/full |
_version_ | 1818725578167025664 |
---|---|
author | Qiuyue Huang Xiaofen Jia Yingming Chu Xuezhi Zhang Hui Ye |
author_facet | Qiuyue Huang Xiaofen Jia Yingming Chu Xuezhi Zhang Hui Ye |
author_sort | Qiuyue Huang |
collection | DOAJ |
description | Helicobacter pylori (H. pylori) has so far infected more than half the global population. It is the most important and controllable risk factor for gastric cancer. The elderly, who are at a higher incidence of the infection, are also commonly found to develop antibiotic resistance. The symptoms, diagnosis, clinical features (of gastric or extra-digestive diseases), and treatment of H. pylori infection in the elderly, are different from that in the non-elderly. Health conditions, including comorbidities and combined medication have limited the use of regular therapies in elderly patients. However, they can still benefit from eradication therapy, thus preventing gastric mucosal lesions and gastric cancer. In addition, new approaches, such as dual therapy and complementary therapy, have the potential to treat older patients with H. pylori infection. |
first_indexed | 2024-12-17T21:44:32Z |
format | Article |
id | doaj.art-f81de6c3b8dd4eb3b8e3e9f18ce0e7de |
institution | Directory Open Access Journal |
issn | 2296-858X |
language | English |
last_indexed | 2024-12-17T21:44:32Z |
publishDate | 2021-09-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Medicine |
spelling | doaj.art-f81de6c3b8dd4eb3b8e3e9f18ce0e7de2022-12-21T21:31:30ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2021-09-01810.3389/fmed.2021.713908713908Helicobacter pylori Infection in Geriatric Patients: Current Situation and Treatment RegimensQiuyue HuangXiaofen JiaYingming ChuXuezhi ZhangHui YeHelicobacter pylori (H. pylori) has so far infected more than half the global population. It is the most important and controllable risk factor for gastric cancer. The elderly, who are at a higher incidence of the infection, are also commonly found to develop antibiotic resistance. The symptoms, diagnosis, clinical features (of gastric or extra-digestive diseases), and treatment of H. pylori infection in the elderly, are different from that in the non-elderly. Health conditions, including comorbidities and combined medication have limited the use of regular therapies in elderly patients. However, they can still benefit from eradication therapy, thus preventing gastric mucosal lesions and gastric cancer. In addition, new approaches, such as dual therapy and complementary therapy, have the potential to treat older patients with H. pylori infection.https://www.frontiersin.org/articles/10.3389/fmed.2021.713908/fullHelicobacter pylorieradication therapystomach cancerdual therapycomplementary therapyelderly |
spellingShingle | Qiuyue Huang Xiaofen Jia Yingming Chu Xuezhi Zhang Hui Ye Helicobacter pylori Infection in Geriatric Patients: Current Situation and Treatment Regimens Frontiers in Medicine Helicobacter pylori eradication therapy stomach cancer dual therapy complementary therapy elderly |
title | Helicobacter pylori Infection in Geriatric Patients: Current Situation and Treatment Regimens |
title_full | Helicobacter pylori Infection in Geriatric Patients: Current Situation and Treatment Regimens |
title_fullStr | Helicobacter pylori Infection in Geriatric Patients: Current Situation and Treatment Regimens |
title_full_unstemmed | Helicobacter pylori Infection in Geriatric Patients: Current Situation and Treatment Regimens |
title_short | Helicobacter pylori Infection in Geriatric Patients: Current Situation and Treatment Regimens |
title_sort | helicobacter pylori infection in geriatric patients current situation and treatment regimens |
topic | Helicobacter pylori eradication therapy stomach cancer dual therapy complementary therapy elderly |
url | https://www.frontiersin.org/articles/10.3389/fmed.2021.713908/full |
work_keys_str_mv | AT qiuyuehuang helicobacterpyloriinfectioningeriatricpatientscurrentsituationandtreatmentregimens AT xiaofenjia helicobacterpyloriinfectioningeriatricpatientscurrentsituationandtreatmentregimens AT yingmingchu helicobacterpyloriinfectioningeriatricpatientscurrentsituationandtreatmentregimens AT xuezhizhang helicobacterpyloriinfectioningeriatricpatientscurrentsituationandtreatmentregimens AT huiye helicobacterpyloriinfectioningeriatricpatientscurrentsituationandtreatmentregimens |