Overexpression of hTERT increases stem-like properties and decreases spontaneous differentiation in human mesenchymal stem cell lines
<p>Abstract</p> <p>To overcome loss of stem-like properties and spontaneous differentiation those hinder the expansion and application of human mesenchymal stem cells (hMSCs), we have clonally isolated permanent and stable human MSC lines by ectopic overexpression of primary cell c...
Main Authors: | Wang Hsei-Wei, Lee Yi-Ting, Liu Hwa-Chung, Chen Chun-Li, Tsai Chih-Chien, Hou Lein-Tuan, Hung Shih-Chieh |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-07-01
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Series: | Journal of Biomedical Science |
Online Access: | http://www.jbiomedsci.com/content/17/1/64 |
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