Comprehensive mutational analysis of the checkpoint signaling function of Rpa1/Ssb1 in fission yeast.
Replication protein A (RPA) is a heterotrimeric complex and the major single-strand DNA (ssDNA) binding protein in eukaryotes. It plays important roles in DNA replication, repair, recombination, telomere maintenance, and checkpoint signaling. Because RPA is essential for cell survival, understanding...
Main Authors: | Yong-Jie Xu, Sankhadip Bhadra, Alaa Taha A Mahdi, Kamal Dev, Ilknur Yurtsever, Toru M Nakamura |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-05-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1010691 |
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