Comprehensive mutational analysis of the checkpoint signaling function of Rpa1/Ssb1 in fission yeast.

Replication protein A (RPA) is a heterotrimeric complex and the major single-strand DNA (ssDNA) binding protein in eukaryotes. It plays important roles in DNA replication, repair, recombination, telomere maintenance, and checkpoint signaling. Because RPA is essential for cell survival, understanding...

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Bibliographic Details
Main Authors: Yong-Jie Xu, Sankhadip Bhadra, Alaa Taha A Mahdi, Kamal Dev, Ilknur Yurtsever, Toru M Nakamura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-05-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010691

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