A Web of Coagulotoxicity: Failure of Antivenom to Neutralize the Destructive (Non-Clotting) Fibrinogenolytic Activity of <i>Loxosceles</i> and <i>Sicarius</i> Spider Venoms

A Web of Coagulotoxicity: Failure of Antivenom to Neutralize the Destructive (Non-Clotting) Fibrinogenolytic Activity of <i>Loxosceles</i> and <i>Sicarius</i> Spider Venoms

Envenomations are complex medical emergencies that can have a range of symptoms and sequelae. The only specific, scientifically-validated treatment for envenomation is antivenom administration, which is designed to alleviate venom effects. A paucity of efficacy testing exists for numerous antivenoms...

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Bibliographic Details
Main Authors: Dwin Grashof, Christina N. Zdenek, James S. Dobson, Nicholas J. Youngman, Francisco Coimbra, Melisa Benard-Valle, Alejandro Alagon, Bryan G. Fry
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Toxins
Subjects:
venom
antivenom
fibrinogen
coagulopathy
spider
Online Access:https://www.mdpi.com/2072-6651/12/2/91

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