Identifying the Need to Discuss Infertility Concerns Affecting Testicular Cancer Patients: An Evaluation (INDICATE Study)
Men with testicular cancer (TC) risk impaired fertility. Fertility is a major concern for TC patients due to diagnosis in almost always reproductive ages and high overall survival. This study assessed counselling in regards to the risk of impaired fertility and sperm cryopreservation. A cross-sectio...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-02-01
|
| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/13/3/553 |
| _version_ | 1797416974035189760 |
|---|---|
| author | Esmée M. Krouwel Thijs G. Jansen Melianthe P. J. Nicolai Sandra W. M. Dieben Saskia A. C. Luelmo Hein Putter Rob C. M. Pelger Henk W. Elzevier |
| author_facet | Esmée M. Krouwel Thijs G. Jansen Melianthe P. J. Nicolai Sandra W. M. Dieben Saskia A. C. Luelmo Hein Putter Rob C. M. Pelger Henk W. Elzevier |
| author_sort | Esmée M. Krouwel |
| collection | DOAJ |
| description | Men with testicular cancer (TC) risk impaired fertility. Fertility is a major concern for TC patients due to diagnosis in almost always reproductive ages and high overall survival. This study assessed counselling in regards to the risk of impaired fertility and sperm cryopreservation. A cross-sectional survey was performed on 566 TC patients diagnosed between 1995–2015. Of the 566 survivors, 201 questionnaires were completed (35.5%). Eighty-eight percent was informed about possible impaired fertility, 9.5% was not informed. The majority (47.3%) preferred the urologist to provide information. Collecting sperm was troublesome but successful for 25.6%, 4.8% did not succeed in collecting sperm. The reasons were high pressure due to disease, pain after surgery and uncomfortable setting. Due to impaired fertility, 19% of the respondents reported grief and 9.3% stated as being less satisfied in life. Sperm cryopreservation was performed by 41.3% (<i>n</i> = 83). One third (<i>n</i> = 63, 31.3%) had children after treatment, of which 11.1% made use of preserved sperm (<i>n</i> = 7). The results of this survey indicate the importance of timely discussion of fertility issues with TC patients. While being discussed with most men, dissatisfaction and grief may occur as a result of impaired fertility and a lack of counselling. Overall, 6.5% made use of cryopreserved sperm (<i>n</i> = 13). Men prefer their urologist providing counselling on fertility. |
| first_indexed | 2024-03-09T06:12:09Z |
| format | Article |
| id | doaj.art-f824d8d9e6a44f178acc2649e55b701a |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-09T06:12:09Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-f824d8d9e6a44f178acc2649e55b701a2023-12-03T11:57:39ZengMDPI AGCancers2072-66942021-02-0113355310.3390/cancers13030553Identifying the Need to Discuss Infertility Concerns Affecting Testicular Cancer Patients: An Evaluation (INDICATE Study)Esmée M. Krouwel0Thijs G. Jansen1Melianthe P. J. Nicolai2Sandra W. M. Dieben3Saskia A. C. Luelmo4Hein Putter5Rob C. M. Pelger6Henk W. Elzevier7Department of Urology, Leiden University Medical Center, 2333 ZA Leiden, The NetherlandsDepartment of Urology, Leiden University Medical Center, 2333 ZA Leiden, The NetherlandsDepartment of Urology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, 1066 CX Amsterdam, The NetherlandsDepartment of Gynaecology, Leiden University Medical Center, 2333 ZA Leiden, The NetherlandsDepartment of Medical Oncology, Leiden University Medical Center, 2333 ZA Leiden, The NetherlandsDepartment of Medical Statistics, Leiden University Medical Center, 2333 ZA Leiden, The NetherlandsDepartment of Urology, Leiden University Medical Center, 2333 ZA Leiden, The NetherlandsDepartment of Urology, Leiden University Medical Center, 2333 ZA Leiden, The NetherlandsMen with testicular cancer (TC) risk impaired fertility. Fertility is a major concern for TC patients due to diagnosis in almost always reproductive ages and high overall survival. This study assessed counselling in regards to the risk of impaired fertility and sperm cryopreservation. A cross-sectional survey was performed on 566 TC patients diagnosed between 1995–2015. Of the 566 survivors, 201 questionnaires were completed (35.5%). Eighty-eight percent was informed about possible impaired fertility, 9.5% was not informed. The majority (47.3%) preferred the urologist to provide information. Collecting sperm was troublesome but successful for 25.6%, 4.8% did not succeed in collecting sperm. The reasons were high pressure due to disease, pain after surgery and uncomfortable setting. Due to impaired fertility, 19% of the respondents reported grief and 9.3% stated as being less satisfied in life. Sperm cryopreservation was performed by 41.3% (<i>n</i> = 83). One third (<i>n</i> = 63, 31.3%) had children after treatment, of which 11.1% made use of preserved sperm (<i>n</i> = 7). The results of this survey indicate the importance of timely discussion of fertility issues with TC patients. While being discussed with most men, dissatisfaction and grief may occur as a result of impaired fertility and a lack of counselling. Overall, 6.5% made use of cryopreserved sperm (<i>n</i> = 13). Men prefer their urologist providing counselling on fertility.https://www.mdpi.com/2072-6694/13/3/553fertility preservationtesticular neoplasmsquality of lifepractice patterns |
| spellingShingle | Esmée M. Krouwel Thijs G. Jansen Melianthe P. J. Nicolai Sandra W. M. Dieben Saskia A. C. Luelmo Hein Putter Rob C. M. Pelger Henk W. Elzevier Identifying the Need to Discuss Infertility Concerns Affecting Testicular Cancer Patients: An Evaluation (INDICATE Study) Cancers fertility preservation testicular neoplasms quality of life practice patterns |
| title | Identifying the Need to Discuss Infertility Concerns Affecting Testicular Cancer Patients: An Evaluation (INDICATE Study) |
| title_full | Identifying the Need to Discuss Infertility Concerns Affecting Testicular Cancer Patients: An Evaluation (INDICATE Study) |
| title_fullStr | Identifying the Need to Discuss Infertility Concerns Affecting Testicular Cancer Patients: An Evaluation (INDICATE Study) |
| title_full_unstemmed | Identifying the Need to Discuss Infertility Concerns Affecting Testicular Cancer Patients: An Evaluation (INDICATE Study) |
| title_short | Identifying the Need to Discuss Infertility Concerns Affecting Testicular Cancer Patients: An Evaluation (INDICATE Study) |
| title_sort | identifying the need to discuss infertility concerns affecting testicular cancer patients an evaluation indicate study |
| topic | fertility preservation testicular neoplasms quality of life practice patterns |
| url | https://www.mdpi.com/2072-6694/13/3/553 |
| work_keys_str_mv | AT esmeemkrouwel identifyingtheneedtodiscussinfertilityconcernsaffectingtesticularcancerpatientsanevaluationindicatestudy AT thijsgjansen identifyingtheneedtodiscussinfertilityconcernsaffectingtesticularcancerpatientsanevaluationindicatestudy AT melianthepjnicolai identifyingtheneedtodiscussinfertilityconcernsaffectingtesticularcancerpatientsanevaluationindicatestudy AT sandrawmdieben identifyingtheneedtodiscussinfertilityconcernsaffectingtesticularcancerpatientsanevaluationindicatestudy AT saskiaacluelmo identifyingtheneedtodiscussinfertilityconcernsaffectingtesticularcancerpatientsanevaluationindicatestudy AT heinputter identifyingtheneedtodiscussinfertilityconcernsaffectingtesticularcancerpatientsanevaluationindicatestudy AT robcmpelger identifyingtheneedtodiscussinfertilityconcernsaffectingtesticularcancerpatientsanevaluationindicatestudy AT henkwelzevier identifyingtheneedtodiscussinfertilityconcernsaffectingtesticularcancerpatientsanevaluationindicatestudy |