AICAR inhibits ceramide biosynthesis in skeletal muscle

AICAR inhibits ceramide biosynthesis in skeletal muscle

<p>Abstract</p> <p>Background</p> <p>The worldwide prevalence of obesity has lead to increased efforts to find therapies to treat obesity-related pathologies. Ceramide is a well-established mediator of several health problems that arise from adipose tissue expansion. Th...

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Bibliographic Details
Main Authors: Erickson Katherine A, Smith Melissa E, Anthonymuthu Tamil S, Evanson Michael J, Brassfield Eric S, Hodson Aimee E, Bressler M, Tucker Braden J, Thatcher Mikayla O, Prince John T, Hancock Chad R, Bikman Benjamin T
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Diabetology & Metabolic Syndrome
Subjects:
AICAR
Ceramide
AMPK
Obesity
Metabolic syndrome
Online Access:http://www.dmsjournal.com/content/4/1/45

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