A genome-wide functional genomics approach uncovers genetic determinants of immune phenotypes in type 1 diabetes

A genome-wide functional genomics approach uncovers genetic determinants of immune phenotypes in type 1 diabetes

Background: The large inter-individual variability in immune-cell composition and function determines immune responses in general and susceptibility o immune-mediated diseases in particular. While much has been learned about the genetic variants relevant for type 1 diabetes (T1D), the pathophysiolog...

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Bibliographic Details
Main Authors: Xiaojing Chu, Anna WM Janssen, Hans Koenen, Linzhung Chang, Xuehui He, Irma Joosten, Rinke Stienstra, Yunus Kuijpers, Cisca Wijmenga, Cheng-Jian Xu, Mihai G Netea, Cees J Tack, Yang Li
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-05-01
Series:eLife
Subjects:
functional genomics
type 1 diabetes
immune function
Online Access:https://elifesciences.org/articles/73709

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