Polarity protein SCRIB interacts with SLC3A2 to regulate proliferation and tamoxifen resistance in ER+ breast cancer
A complex involving polarity protein SCRIB and the leucine amino acid transporter SLC7A5 promotes cell proliferation and tamoxifen resistance in estrogen receptor-positive breast cancer cells.
Main Authors: | Yasuhiro Saito, Shiori Matsuda, Naomi Ohnishi, Keiko Endo, Sanae Ashitani, Maki Ohishi, Ayano Ueno, Masaru Tomita, Koji Ueda, Tomoyoshi Soga, Senthil K. Muthuswamy |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-05-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-022-03363-3 |
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