A fungal NRPS-PKS enzyme catalyses the formation of the flavonoid naringenin
Biosynthesis of the flavonoid naringenin in plants and bacteria is commonly catalysed by a type III polyketide synthase (PKS) using one p-coumaroyl-CoA and three malonyl-CoA molecules as substrates. Here, the authors report a fungal non-ribosomal peptide synthetase PKS hybrid FnsA catalysing the for...
Main Authors: | Hongjiao Zhang, Zixin Li, Shuang Zhou, Shu-Ming Li, Huomiao Ran, Zili Song, Tao Yu, Wen-Bing Yin |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-10-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-34150-7 |
Similar Items
-
Characterization of a NRPS-like Protein from <i>Pestalotiopsis fici</i> for Aldehyde Generation
by: Yuanyuan Li, et al.
Published: (2022-09-01) -
Identification of PKS-NRPS Hybrid Metabolites in Marine-Derived <i>Penicillium oxalicum</i>
by: Hongcheng Li, et al.
Published: (2022-08-01) -
Bioactive PKS–NRPS Alkaloids from the Plant-Derived Endophytic Fungus <i>Xylaria arbuscula</i>
by: Ya Wang, et al.
Published: (2021-12-01) -
Mining and characterization of the PKS–NRPS hybrid for epicoccamide A: a mannosylated tetramate derivative from Epicoccum sp. CPCC 400996
by: Tao Zhang, et al.
Published: (2022-11-01) -
Profile of PKS and NRPS Gene Clusters in the Genome of <i>Streptomyces cellostaticus</i> NBRC 12849<sup>T</sup>
by: Hisayuki Komaki, et al.
Published: (2023-10-01)