Mini-review: advances in 3D bioprinting of vascularized constructs

Abstract 3D in vitro constructs have gained more and more relevance in tissue engineering and in cancer-modeling. In recent years, with the development of thicker and more physiologically relevant tissue patches, the integration of a vascular network has become pivotal, both for sustaining the const...

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Bibliographic Details
Main Authors: Lorenzo Bova, Fabrizio Billi, Elisa Cimetta
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Biology Direct
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13062-020-00273-4
Description
Summary:Abstract 3D in vitro constructs have gained more and more relevance in tissue engineering and in cancer-modeling. In recent years, with the development of thicker and more physiologically relevant tissue patches, the integration of a vascular network has become pivotal, both for sustaining the construct in vitro and to help the integration with the host tissue once implanted. Since 3D bioprinting is rising to be one of the most versatile methods to create vascularized constructs, we here briefly review the most promising advances in bioprinting techniques.
ISSN:1745-6150