The Role of Genetic Risk Factors in Pathogenesis of Childhood-Onset Systemic Lupus Erythematosus

The Role of Genetic Risk Factors in Pathogenesis of Childhood-Onset Systemic Lupus Erythematosus

The pathogenesis of childhood-onset systemic lupus erythematosus (cSLE) is complex and not fully understood. It involves three key factors: genetic risk factors, epigenetic mechanisms, and environmental triggers. Genetic factors play a significant role in the development of the disease, particularly...

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Bibliographic Details
Main Authors: Mario Sestan, Nastasia Kifer, Todor Arsov, Matthew Cook, Julia Ellyard, Carola G. Vinuesa, Marija Jelusic
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Current Issues in Molecular Biology
Subjects:
childhood-onset systemic lupus erythematosus
monogenic systemic lupus erythematosus
genetics
pathogenesis
Online Access:https://www.mdpi.com/1467-3045/45/7/378

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