Induction of cytokines via NF-κB and p38 MAP kinase signalling pathways associated with the immunomodulation by Lactobacillus plantarum NDC 75017 in vitro and in vivo

Induction of cytokines via NF-κB and p38 MAP kinase signalling pathways associated with the immunomodulation by Lactobacillus plantarum NDC 75017 in vitro and in vivo

Lactobacillus has been used as a functional food ingredient to improve health. The expression of the pro-inflammatory cytokines interleukin-1β (IL-1β), IL-6 and tumour necrosis factor-α (TNF-α) stimulated by Lactobacillus plantarum NDC 75017 were investigated in the Caco-2 cells and intestinal tract...

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Bibliographic Details
Main Authors: Yujun Jiang, Li Li, Haoxiu Sun, Yi Shan, Ying Liu, Liang Li, Bo Qu, Chaoxin Man
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Journal of Functional Foods
Subjects:
Cytokines
Intestinal epithelium cells
Lactobacillus plantarum
Immunomodulatory effects
NF-κB
p38 MAPK
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615005241

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