Caspase 6 promotes innate immune activation by functional crosstalk between RIPK1-IκBα axis in liver inflammation
Abstract Background Caspase 6 is an essential regulator in innate immunity, inflammasome activation and host defense. We aimed to characterize the causal mechanism of Caspase 6 in liver sterile inflammatory injury. Methods Human liver tissues were harvested from patients undergoing ischemia-related...
Main Authors: | Yuanbang Lin, Mingwei Sheng, Hua Qin, Peng Zhang, Chunli Wang, Wei Fu, Xiangjun Meng, Duowei Wang, Yachao Hou |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-10-01
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Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12964-023-01287-x |
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