Effects of a blood flow restriction exercise under different pressures on testosterone, growth hormone, and insulin-like growth factor levels

Objective To investigate the changes in serum growth hormone (GH), testosterone, and insulin-like growth factor 1 (IGF-1) during low-intensity resistance exercise under different cuff pressures. Methods We performed a single-blind, cross-over design study. Twenty-five healthy young men performed thr...

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Main Authors: Li Yinghao, Yang Jing, Wang Yongqi, Zhou Jianming, Gao Zeng, Tang Yiting, Li Shuoqi
Format: Article
Language:English
Published: SAGE Publishing 2021-09-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605211039564
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author Li Yinghao
Yang Jing
Wang Yongqi
Zhou Jianming
Gao Zeng
Tang Yiting
Li Shuoqi
author_facet Li Yinghao
Yang Jing
Wang Yongqi
Zhou Jianming
Gao Zeng
Tang Yiting
Li Shuoqi
author_sort Li Yinghao
collection DOAJ
description Objective To investigate the changes in serum growth hormone (GH), testosterone, and insulin-like growth factor 1 (IGF-1) during low-intensity resistance exercise under different cuff pressures. Methods We performed a single-blind, cross-over design study. Twenty-five healthy young men performed three exercise protocols as follows: 1) no blood flow restriction exercise (control group), 2) resistance exercise at 40% of arterial occlusion pressure (AOP) (low group), and 3) resistance exercise at 70% of AOP (high group). Blood lactate, GH, testosterone, and IGF-1 levels were measured at four time points. Results There were no differences in the indices before exercise. The blood flow restriction exercise under different pressures had different effects on each index and there was an interactive effect. GH levels were significantly higher in the high group than in the other groups after exercise. Immediately after exercise, IGF-1 and testosterone levels were significantly higher in the high group than in the other groups. At 15 minutes after exercise, testosterone levels were significantly higher in the high group than in the other groups. Conclusions Low-intensity resistance exercise combined with blood flow restriction effectively increases GH, IGF-1, and testosterone levels in young men. Increasing the cuff pressure results in greater levels of hormone secretion.
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spelling doaj.art-f8388153ac524b8b805453219a05c7d22022-12-21T21:55:42ZengSAGE PublishingJournal of International Medical Research1473-23002021-09-014910.1177/03000605211039564Effects of a blood flow restriction exercise under different pressures on testosterone, growth hormone, and insulin-like growth factor levelsLi YinghaoYang JingWang YongqiZhou JianmingGao ZengTang YitingLi ShuoqiObjective To investigate the changes in serum growth hormone (GH), testosterone, and insulin-like growth factor 1 (IGF-1) during low-intensity resistance exercise under different cuff pressures. Methods We performed a single-blind, cross-over design study. Twenty-five healthy young men performed three exercise protocols as follows: 1) no blood flow restriction exercise (control group), 2) resistance exercise at 40% of arterial occlusion pressure (AOP) (low group), and 3) resistance exercise at 70% of AOP (high group). Blood lactate, GH, testosterone, and IGF-1 levels were measured at four time points. Results There were no differences in the indices before exercise. The blood flow restriction exercise under different pressures had different effects on each index and there was an interactive effect. GH levels were significantly higher in the high group than in the other groups after exercise. Immediately after exercise, IGF-1 and testosterone levels were significantly higher in the high group than in the other groups. At 15 minutes after exercise, testosterone levels were significantly higher in the high group than in the other groups. Conclusions Low-intensity resistance exercise combined with blood flow restriction effectively increases GH, IGF-1, and testosterone levels in young men. Increasing the cuff pressure results in greater levels of hormone secretion.https://doi.org/10.1177/03000605211039564
spellingShingle Li Yinghao
Yang Jing
Wang Yongqi
Zhou Jianming
Gao Zeng
Tang Yiting
Li Shuoqi
Effects of a blood flow restriction exercise under different pressures on testosterone, growth hormone, and insulin-like growth factor levels
Journal of International Medical Research
title Effects of a blood flow restriction exercise under different pressures on testosterone, growth hormone, and insulin-like growth factor levels
title_full Effects of a blood flow restriction exercise under different pressures on testosterone, growth hormone, and insulin-like growth factor levels
title_fullStr Effects of a blood flow restriction exercise under different pressures on testosterone, growth hormone, and insulin-like growth factor levels
title_full_unstemmed Effects of a blood flow restriction exercise under different pressures on testosterone, growth hormone, and insulin-like growth factor levels
title_short Effects of a blood flow restriction exercise under different pressures on testosterone, growth hormone, and insulin-like growth factor levels
title_sort effects of a blood flow restriction exercise under different pressures on testosterone growth hormone and insulin like growth factor levels
url https://doi.org/10.1177/03000605211039564
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