Helminth contamination of Wild Ruminants in the West kazakhstan Region and activity of the supramolecular complex of albendazole with Polyvinylpyrrolidone at helminthoses
The purpose of the research is to establish the species composition and contamination of saigas with the main helminths, as well as to determine the effectiveness of the supramolecular complex of albendazole with polyvinylpyrrolidone at helminthoses in the conditions of the West Kazakhstan region. M...
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| Format: | Article |
| Language: | Russian |
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Federal Scientific Centre VIEV
2020-06-01
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| Series: | Российский паразитологический журнал |
| Subjects: | |
| Online Access: | https://vniigis.elpub.ru/jour/article/view/592 |
| _version_ | 1797270528040370176 |
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| author | R. S. Karmaliyev I. A. Arkhipov B. M. Sidikhov Zh. T. Usenov B. O. Ertleuova D. E. Gabdullin |
| author_facet | R. S. Karmaliyev I. A. Arkhipov B. M. Sidikhov Zh. T. Usenov B. O. Ertleuova D. E. Gabdullin |
| author_sort | R. S. Karmaliyev |
| collection | DOAJ |
| description | The purpose of the research is to establish the species composition and contamination of saigas with the main helminths, as well as to determine the effectiveness of the supramolecular complex of albendazole with polyvinylpyrrolidone at helminthoses in the conditions of the West Kazakhstan region. Materials and methods. Incomplete helminthological autopsy according to K. I. Skryabin was used to study the contamination of saigas with helminths. Supramolecular complex of albendazole with polyvinylpyrrolidone was tested on 30 saigas spontaneously infected with gastrointestinal strongylates and Moniezia spp. Animals of different groups of 10 animals each were administered orally the supramolecular complex of albendazole with polyvinylpyrrolidone at a single dose of 2.0 mg/kg of the AS compared with the base drug albendazole in a dose of 7.5 mg/kg of the AS. The control was a group of saigas that did not receive the drug. The effectiveness of the drugs was considered according to the data of coproovoscopic studies of saigas by the flotation method before and 14 days after administration. Results and discussion. The prevalence of saiga infection with Moniezia spp. in the West Kazakhstan region averaged 37%, Echinococcus sp. 25, Trychostrongilus spp. 62, Ostertagia spp. 87, Marshallagia sp. 87, Haemonchus sp. 75, Nematodirus spp. 87 and Trichocephalus spp. 25%. The 100 % efficiency of the supramolecular complex of albendazole with polyvinylpyrrolidone was obtained at strongylatosis of the gastrointestinal tract and monieziosis of saigas at a dose of 2.0 mg/kg of the AS according to the studies of fecal samples with 80–70% effectiveness of the base drug. |
| first_indexed | 2024-03-08T21:41:40Z |
| format | Article |
| id | doaj.art-f83c1298c7284c6c8a1a86791b65d596 |
| institution | Directory Open Access Journal |
| issn | 1998-8435 2541-7843 |
| language | Russian |
| last_indexed | 2024-04-25T02:05:42Z |
| publishDate | 2020-06-01 |
| publisher | Federal Scientific Centre VIEV |
| record_format | Article |
| series | Российский паразитологический журнал |
| spelling | doaj.art-f83c1298c7284c6c8a1a86791b65d5962024-03-07T14:34:30ZrusFederal Scientific Centre VIEVРоссийский паразитологический журнал1998-84352541-78432020-06-01142323710.31016/1998-8435-2020-14-2-32-37575Helminth contamination of Wild Ruminants in the West kazakhstan Region and activity of the supramolecular complex of albendazole with Polyvinylpyrrolidone at helminthosesR. S. Karmaliyev0I. A. Arkhipov1B. M. Sidikhov2Zh. T. Usenov3B. O. Ertleuova4D. E. Gabdullin5West Kazakhstan Agrarian and Technical University named after Zhangir KhanAll-Russian Scientific Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientific Institution "Federal Scientific Centre VIEV"West Kazakhstan Agrarian and Technical University named after Zhangir KhanWest Kazakhstan Agrarian and Technical University named after Zhangir KhanWest Kazakhstan Agrarian and Technical University named after Zhangir KhanWest Kazakhstan Agrarian and Technical University named after Zhangir KhanThe purpose of the research is to establish the species composition and contamination of saigas with the main helminths, as well as to determine the effectiveness of the supramolecular complex of albendazole with polyvinylpyrrolidone at helminthoses in the conditions of the West Kazakhstan region. Materials and methods. Incomplete helminthological autopsy according to K. I. Skryabin was used to study the contamination of saigas with helminths. Supramolecular complex of albendazole with polyvinylpyrrolidone was tested on 30 saigas spontaneously infected with gastrointestinal strongylates and Moniezia spp. Animals of different groups of 10 animals each were administered orally the supramolecular complex of albendazole with polyvinylpyrrolidone at a single dose of 2.0 mg/kg of the AS compared with the base drug albendazole in a dose of 7.5 mg/kg of the AS. The control was a group of saigas that did not receive the drug. The effectiveness of the drugs was considered according to the data of coproovoscopic studies of saigas by the flotation method before and 14 days after administration. Results and discussion. The prevalence of saiga infection with Moniezia spp. in the West Kazakhstan region averaged 37%, Echinococcus sp. 25, Trychostrongilus spp. 62, Ostertagia spp. 87, Marshallagia sp. 87, Haemonchus sp. 75, Nematodirus spp. 87 and Trichocephalus spp. 25%. The 100 % efficiency of the supramolecular complex of albendazole with polyvinylpyrrolidone was obtained at strongylatosis of the gastrointestinal tract and monieziosis of saigas at a dose of 2.0 mg/kg of the AS according to the studies of fecal samples with 80–70% effectiveness of the base drug.https://vniigis.elpub.ru/jour/article/view/592saigashelminthsinfectionalbendazolesupramolecular complexpolyvinylpyrrolidoneefficiencywestkazakhstan region |
| spellingShingle | R. S. Karmaliyev I. A. Arkhipov B. M. Sidikhov Zh. T. Usenov B. O. Ertleuova D. E. Gabdullin Helminth contamination of Wild Ruminants in the West kazakhstan Region and activity of the supramolecular complex of albendazole with Polyvinylpyrrolidone at helminthoses Российский паразитологический журнал saigas helminths infection albendazole supramolecular complex polyvinylpyrrolidone efficiency westkazakhstan region |
| title | Helminth contamination of Wild Ruminants in the West kazakhstan Region and activity of the supramolecular complex of albendazole with Polyvinylpyrrolidone at helminthoses |
| title_full | Helminth contamination of Wild Ruminants in the West kazakhstan Region and activity of the supramolecular complex of albendazole with Polyvinylpyrrolidone at helminthoses |
| title_fullStr | Helminth contamination of Wild Ruminants in the West kazakhstan Region and activity of the supramolecular complex of albendazole with Polyvinylpyrrolidone at helminthoses |
| title_full_unstemmed | Helminth contamination of Wild Ruminants in the West kazakhstan Region and activity of the supramolecular complex of albendazole with Polyvinylpyrrolidone at helminthoses |
| title_short | Helminth contamination of Wild Ruminants in the West kazakhstan Region and activity of the supramolecular complex of albendazole with Polyvinylpyrrolidone at helminthoses |
| title_sort | helminth contamination of wild ruminants in the west kazakhstan region and activity of the supramolecular complex of albendazole with polyvinylpyrrolidone at helminthoses |
| topic | saigas helminths infection albendazole supramolecular complex polyvinylpyrrolidone efficiency westkazakhstan region |
| url | https://vniigis.elpub.ru/jour/article/view/592 |
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