The prevalence of IGM antibodies to Zika virus in pregnant women in Northern Nigeria
Introduction. Zika virus (ZIKV) infection during pregnancy can result in severe outcomes for both the pregnant woman and the developing fetus. The objective of this study was to investigate the prevalence of Zika virus infection among pregnant women who sought healthcare services at Ahmadu Bello...
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| Format: | Article |
| Language: | English |
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Central Research Institute for Epidemiology
2023-05-01
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| Series: | Вопросы вирусологии |
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| Online Access: | https://virusjour.crie.ru/jour/article/viewFile/2520/448 |
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| author | Hafeez Aderinsayo Adekola David Ajiboye Ojo Saka Adebayo Balogun Morenike Aderonke Dipeolu Musa Mohammed Daniel Stephen Adejo Rabi'at Muhammad Aliyu Mohammed Asara Abdullahi Nana Hawwa Madugu |
| author_facet | Hafeez Aderinsayo Adekola David Ajiboye Ojo Saka Adebayo Balogun Morenike Aderonke Dipeolu Musa Mohammed Daniel Stephen Adejo Rabi'at Muhammad Aliyu Mohammed Asara Abdullahi Nana Hawwa Madugu |
| author_sort | Hafeez Aderinsayo Adekola |
| collection | DOAJ |
| description | Introduction. Zika virus (ZIKV) infection during pregnancy can result in severe outcomes for both the pregnant woman and the developing fetus.
The objective of this study was to investigate the prevalence of Zika virus infection among pregnant women who sought healthcare services at Ahmadu Bello University Teaching Hospital.
Materials and methods. Serum samples were collected and analyzed using Enzyme Linked Immunoassay and RT-qPCR methods, while a structured questionnaire was used to gather relevant information about the participants.
Results. The results showed that 53 out of the 180 pregnant women tested positive for Anti-Zika IgM antibodies, which represents a 29.4% prevalence rate. Subsequent RT-qPCR analysis found that only 6 out of the 53 positive samples contained Zika virus RNA. Fever and headache were the most commonly reported symptoms related to the infection.
Conclusion. These findings indicate a potential outbreak of Zika fever in Northern Nigeria emphasizing the importance for pregnant women to take precautions to avoid getting infected. |
| first_indexed | 2024-03-13T00:09:14Z |
| format | Article |
| id | doaj.art-f83f25be50364327bdde7b834b9cfdc9 |
| institution | Directory Open Access Journal |
| issn | 0507-4088 2411-2097 |
| language | English |
| last_indexed | 2024-03-13T00:09:14Z |
| publishDate | 2023-05-01 |
| publisher | Central Research Institute for Epidemiology |
| record_format | Article |
| series | Вопросы вирусологии |
| spelling | doaj.art-f83f25be50364327bdde7b834b9cfdc92023-07-12T19:32:23ZengCentral Research Institute for EpidemiologyВопросы вирусологии0507-40882411-20972023-05-0168211712310.36233/0507-4088-162481The prevalence of IGM antibodies to Zika virus in pregnant women in Northern NigeriaHafeez Aderinsayo Adekola0https://orcid.org/0000-0003-3132-3315David Ajiboye Ojo1https://orcid.org/0000-0001-5762-7689Saka Adebayo Balogun2https://orcid.org/0000-0002-0045-602XMorenike Aderonke Dipeolu3https://orcid.org/0000-0002-8479-6135Musa Mohammed4https://orcid.org/0000-0001-5240-2130Daniel Stephen Adejo5https://orcid.org/0000-0003-0246-0767Rabi'at Muhammad Aliyu6https://orcid.org/0000-0001-5735-9709Mohammed Asara Abdullahi7https://orcid.org/0000-0003-3820-8264Nana Hawwa Madugu8https://orcid.org/0000-0002-8832-4215Olabisi Onabanjo UniversityFederal University of AgricultureFederal University of AgricultureFederal University of AgricultureAhmadu Bello UniversityAhmadu Bello UniversityAhmadu Bello University Teaching HospitalAhmadu Bello University Teaching HospitalAhmadu Bello University Teaching HospitalIntroduction. Zika virus (ZIKV) infection during pregnancy can result in severe outcomes for both the pregnant woman and the developing fetus. The objective of this study was to investigate the prevalence of Zika virus infection among pregnant women who sought healthcare services at Ahmadu Bello University Teaching Hospital. Materials and methods. Serum samples were collected and analyzed using Enzyme Linked Immunoassay and RT-qPCR methods, while a structured questionnaire was used to gather relevant information about the participants. Results. The results showed that 53 out of the 180 pregnant women tested positive for Anti-Zika IgM antibodies, which represents a 29.4% prevalence rate. Subsequent RT-qPCR analysis found that only 6 out of the 53 positive samples contained Zika virus RNA. Fever and headache were the most commonly reported symptoms related to the infection. Conclusion. These findings indicate a potential outbreak of Zika fever in Northern Nigeria emphasizing the importance for pregnant women to take precautions to avoid getting infected.https://virusjour.crie.ru/jour/article/viewFile/2520/448zika virus infectionnigeriaexamination of pregnant womenmac-elisart-qpcranti-zika igm antibodies |
| spellingShingle | Hafeez Aderinsayo Adekola David Ajiboye Ojo Saka Adebayo Balogun Morenike Aderonke Dipeolu Musa Mohammed Daniel Stephen Adejo Rabi'at Muhammad Aliyu Mohammed Asara Abdullahi Nana Hawwa Madugu The prevalence of IGM antibodies to Zika virus in pregnant women in Northern Nigeria Вопросы вирусологии zika virus infection nigeria examination of pregnant women mac-elisa rt-qpcr anti-zika igm antibodies |
| title | The prevalence of IGM antibodies to Zika virus in pregnant women in Northern Nigeria |
| title_full | The prevalence of IGM antibodies to Zika virus in pregnant women in Northern Nigeria |
| title_fullStr | The prevalence of IGM antibodies to Zika virus in pregnant women in Northern Nigeria |
| title_full_unstemmed | The prevalence of IGM antibodies to Zika virus in pregnant women in Northern Nigeria |
| title_short | The prevalence of IGM antibodies to Zika virus in pregnant women in Northern Nigeria |
| title_sort | prevalence of igm antibodies to zika virus in pregnant women in northern nigeria |
| topic | zika virus infection nigeria examination of pregnant women mac-elisa rt-qpcr anti-zika igm antibodies |
| url | https://virusjour.crie.ru/jour/article/viewFile/2520/448 |
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