State of the Art of Pharmacological Activators of p53 in Ocular Malignancies

State of the Art of Pharmacological Activators of p53 in Ocular Malignancies

The pivotal role of p53 in the regulation of a vast array of cellular functions has been the subject of extensive research. The biological activity of p53 is not strictly limited to cell cycle arrest but also includes the regulation of homeostasis, DNA repair, apoptosis, and senescence. Thus, mutati...

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Bibliographic Details
Main Authors: Fabio Casciano, Enrico Zauli, Massimo Busin, Lorenzo Caruso, Saleh AlMesfer, Samar Al-Swailem, Giorgio Zauli, Angeli Christy Yu
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cancers
Subjects:
p53 pathways
ocular malignancies
therapy
retinoblastoma
uveal melanoma
conjunctival melanoma
Online Access:https://www.mdpi.com/2072-6694/15/14/3593

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