RNA Phage VLP-Based Vaccine Platforms

Virus-like particles from a variety of RNA bacteriophages have turned out to be useful platforms for delivery of vaccine antigens in a highly immunogenic format. Here we update the current state of development of RNA phage VLPs as platforms for presentation of diverse antigens by genetic, enzymatic,...

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Main Authors: David S. Peabody, Julianne Peabody, Steven B. Bradfute, Bryce Chackerian
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/14/8/764
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author David S. Peabody
Julianne Peabody
Steven B. Bradfute
Bryce Chackerian
author_facet David S. Peabody
Julianne Peabody
Steven B. Bradfute
Bryce Chackerian
author_sort David S. Peabody
collection DOAJ
description Virus-like particles from a variety of RNA bacteriophages have turned out to be useful platforms for delivery of vaccine antigens in a highly immunogenic format. Here we update the current state of development of RNA phage VLPs as platforms for presentation of diverse antigens by genetic, enzymatic, and chemical display methods.
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spelling doaj.art-f84553065efb438bab808d9a6ba2f0d22023-11-22T09:11:28ZengMDPI AGPharmaceuticals1424-82472021-08-0114876410.3390/ph14080764RNA Phage VLP-Based Vaccine PlatformsDavid S. Peabody0Julianne Peabody1Steven B. Bradfute2Bryce Chackerian3Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USADepartment of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USACenter for Global Health, Division of Infectious Diseases, Department of Internal Medicine, University of New Mexico, Albuquerque, NM 505, USADepartment of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USAVirus-like particles from a variety of RNA bacteriophages have turned out to be useful platforms for delivery of vaccine antigens in a highly immunogenic format. Here we update the current state of development of RNA phage VLPs as platforms for presentation of diverse antigens by genetic, enzymatic, and chemical display methods.https://www.mdpi.com/1424-8247/14/8/764virus-like particleVLPRNA bacteriophagevaccines
spellingShingle David S. Peabody
Julianne Peabody
Steven B. Bradfute
Bryce Chackerian
RNA Phage VLP-Based Vaccine Platforms
Pharmaceuticals
virus-like particle
VLP
RNA bacteriophage
vaccines
title RNA Phage VLP-Based Vaccine Platforms
title_full RNA Phage VLP-Based Vaccine Platforms
title_fullStr RNA Phage VLP-Based Vaccine Platforms
title_full_unstemmed RNA Phage VLP-Based Vaccine Platforms
title_short RNA Phage VLP-Based Vaccine Platforms
title_sort rna phage vlp based vaccine platforms
topic virus-like particle
VLP
RNA bacteriophage
vaccines
url https://www.mdpi.com/1424-8247/14/8/764
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