RNA Phage VLP-Based Vaccine Platforms
Virus-like particles from a variety of RNA bacteriophages have turned out to be useful platforms for delivery of vaccine antigens in a highly immunogenic format. Here we update the current state of development of RNA phage VLPs as platforms for presentation of diverse antigens by genetic, enzymatic,...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
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MDPI AG
2021-08-01
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Series: | Pharmaceuticals |
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Online Access: | https://www.mdpi.com/1424-8247/14/8/764 |
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author | David S. Peabody Julianne Peabody Steven B. Bradfute Bryce Chackerian |
author_facet | David S. Peabody Julianne Peabody Steven B. Bradfute Bryce Chackerian |
author_sort | David S. Peabody |
collection | DOAJ |
description | Virus-like particles from a variety of RNA bacteriophages have turned out to be useful platforms for delivery of vaccine antigens in a highly immunogenic format. Here we update the current state of development of RNA phage VLPs as platforms for presentation of diverse antigens by genetic, enzymatic, and chemical display methods. |
first_indexed | 2024-03-10T08:29:48Z |
format | Article |
id | doaj.art-f84553065efb438bab808d9a6ba2f0d2 |
institution | Directory Open Access Journal |
issn | 1424-8247 |
language | English |
last_indexed | 2024-03-10T08:29:48Z |
publishDate | 2021-08-01 |
publisher | MDPI AG |
record_format | Article |
series | Pharmaceuticals |
spelling | doaj.art-f84553065efb438bab808d9a6ba2f0d22023-11-22T09:11:28ZengMDPI AGPharmaceuticals1424-82472021-08-0114876410.3390/ph14080764RNA Phage VLP-Based Vaccine PlatformsDavid S. Peabody0Julianne Peabody1Steven B. Bradfute2Bryce Chackerian3Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USADepartment of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USACenter for Global Health, Division of Infectious Diseases, Department of Internal Medicine, University of New Mexico, Albuquerque, NM 505, USADepartment of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USAVirus-like particles from a variety of RNA bacteriophages have turned out to be useful platforms for delivery of vaccine antigens in a highly immunogenic format. Here we update the current state of development of RNA phage VLPs as platforms for presentation of diverse antigens by genetic, enzymatic, and chemical display methods.https://www.mdpi.com/1424-8247/14/8/764virus-like particleVLPRNA bacteriophagevaccines |
spellingShingle | David S. Peabody Julianne Peabody Steven B. Bradfute Bryce Chackerian RNA Phage VLP-Based Vaccine Platforms Pharmaceuticals virus-like particle VLP RNA bacteriophage vaccines |
title | RNA Phage VLP-Based Vaccine Platforms |
title_full | RNA Phage VLP-Based Vaccine Platforms |
title_fullStr | RNA Phage VLP-Based Vaccine Platforms |
title_full_unstemmed | RNA Phage VLP-Based Vaccine Platforms |
title_short | RNA Phage VLP-Based Vaccine Platforms |
title_sort | rna phage vlp based vaccine platforms |
topic | virus-like particle VLP RNA bacteriophage vaccines |
url | https://www.mdpi.com/1424-8247/14/8/764 |
work_keys_str_mv | AT davidspeabody rnaphagevlpbasedvaccineplatforms AT juliannepeabody rnaphagevlpbasedvaccineplatforms AT stevenbbradfute rnaphagevlpbasedvaccineplatforms AT brycechackerian rnaphagevlpbasedvaccineplatforms |