A Novel Microfluidic Cell Co-Culture Platform for the Study of the Molecular Mechanisms of Parkinson’s Disease and other Synucleinopathies
Although the precise molecular mechanisms underlying Parkinson’s disease (PD) are still elusive, it is now known that spreading of alpha-synuclein (aSyn) pathology and neuroinflammation are important players in disease progression. Here, we developed a novel microfluidic cell-culture platform for st...
Main Authors: | João Tiago Fernandes, Oldriska Chutna, Virginia Chu, João Pedro Conde, Tiago Fleming Outeiro |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-11-01
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Series: | Frontiers in Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00511/full |
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