Highly Luminescent Nucleoside-Based N, P-Doped Carbon Dots for Sensitive Detection of Ions and Bioimaging
The efficient detection of Fe3+ and MnO4− in a water environment is very important and challenging due to their harmful effects on the health of humanity and environmental systems. Good biocompatibility, sensitivity, selectivity, and superior photophysical properties were important attributes of car...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-06-01
|
| Series: | Frontiers in Chemistry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2022.906806/full |
| _version_ | 1818468931633938432 |
|---|---|
| author | Mengru Wang Mengling Liu Shuli Nong Wenzhu Song Xianpeng Zhang Shuang Shen Guohong Jian Xiangyao Chen Zhanchao Li Li Xu Li Xu |
| author_facet | Mengru Wang Mengling Liu Shuli Nong Wenzhu Song Xianpeng Zhang Shuang Shen Guohong Jian Xiangyao Chen Zhanchao Li Li Xu Li Xu |
| author_sort | Mengru Wang |
| collection | DOAJ |
| description | The efficient detection of Fe3+ and MnO4− in a water environment is very important and challenging due to their harmful effects on the health of humanity and environmental systems. Good biocompatibility, sensitivity, selectivity, and superior photophysical properties were important attributes of carbon dot-based CDs sensors for sensing applications. In this work, we synthesized N, P-co-doped carbon dots (N/P CDs) with guanosine 5′-monophosphate (GMP) as a green carbon source, with high fluorescence quantum yield in water (QY, 53.72%). First, the luminescent N/P CDs showed a three-state “on-off-on” fluorescence response upon the sequential addition of Fe3+ and F−, with a low detection limit of 12 nM for Fe3+ and 8.5 nM for F−, respectively. Second, the N/P CDs also exhibited desirable selectivity and sensitivity for toxic MnO4− detection with the limit of detection of 18.2 nM, through a turn-off mechanism. Moreover, the luminescent N/P CDs successfully monitored the aforementioned ions in environmental water samples and in Escherichia coli. |
| first_indexed | 2024-04-13T21:18:13Z |
| format | Article |
| id | doaj.art-f849429ab5544f60ba1d96bee9a003cc |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-04-13T21:18:13Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-f849429ab5544f60ba1d96bee9a003cc2022-12-22T02:29:37ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462022-06-011010.3389/fchem.2022.906806906806Highly Luminescent Nucleoside-Based N, P-Doped Carbon Dots for Sensitive Detection of Ions and BioimagingMengru Wang0Mengling Liu1Shuli Nong2Wenzhu Song3Xianpeng Zhang4Shuang Shen5Guohong Jian6Xiangyao Chen7Zhanchao Li8Li Xu9Li Xu10School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan, ChinaSchool of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan, ChinaSchool of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan, ChinaSchool of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan, ChinaSchool of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan, ChinaSchool of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan, ChinaSchool of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan, ChinaSchool of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan, ChinaSchool of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan, ChinaSchool of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan, ChinaGuangdong Pharmaceutical University−University of Hong Kong Joint Biomedical Innovation Platform, Zhongshan, ChinaThe efficient detection of Fe3+ and MnO4− in a water environment is very important and challenging due to their harmful effects on the health of humanity and environmental systems. Good biocompatibility, sensitivity, selectivity, and superior photophysical properties were important attributes of carbon dot-based CDs sensors for sensing applications. In this work, we synthesized N, P-co-doped carbon dots (N/P CDs) with guanosine 5′-monophosphate (GMP) as a green carbon source, with high fluorescence quantum yield in water (QY, 53.72%). First, the luminescent N/P CDs showed a three-state “on-off-on” fluorescence response upon the sequential addition of Fe3+ and F−, with a low detection limit of 12 nM for Fe3+ and 8.5 nM for F−, respectively. Second, the N/P CDs also exhibited desirable selectivity and sensitivity for toxic MnO4− detection with the limit of detection of 18.2 nM, through a turn-off mechanism. Moreover, the luminescent N/P CDs successfully monitored the aforementioned ions in environmental water samples and in Escherichia coli.https://www.frontiersin.org/articles/10.3389/fchem.2022.906806/fullN/P co-dopingcarbon dotsFe3+ detectionMnO4−bacteria imaging |
| spellingShingle | Mengru Wang Mengling Liu Shuli Nong Wenzhu Song Xianpeng Zhang Shuang Shen Guohong Jian Xiangyao Chen Zhanchao Li Li Xu Li Xu Highly Luminescent Nucleoside-Based N, P-Doped Carbon Dots for Sensitive Detection of Ions and Bioimaging Frontiers in Chemistry N/P co-doping carbon dots Fe3+ detection MnO4− bacteria imaging |
| title | Highly Luminescent Nucleoside-Based N, P-Doped Carbon Dots for Sensitive Detection of Ions and Bioimaging |
| title_full | Highly Luminescent Nucleoside-Based N, P-Doped Carbon Dots for Sensitive Detection of Ions and Bioimaging |
| title_fullStr | Highly Luminescent Nucleoside-Based N, P-Doped Carbon Dots for Sensitive Detection of Ions and Bioimaging |
| title_full_unstemmed | Highly Luminescent Nucleoside-Based N, P-Doped Carbon Dots for Sensitive Detection of Ions and Bioimaging |
| title_short | Highly Luminescent Nucleoside-Based N, P-Doped Carbon Dots for Sensitive Detection of Ions and Bioimaging |
| title_sort | highly luminescent nucleoside based n p doped carbon dots for sensitive detection of ions and bioimaging |
| topic | N/P co-doping carbon dots Fe3+ detection MnO4− bacteria imaging |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2022.906806/full |
| work_keys_str_mv | AT mengruwang highlyluminescentnucleosidebasednpdopedcarbondotsforsensitivedetectionofionsandbioimaging AT menglingliu highlyluminescentnucleosidebasednpdopedcarbondotsforsensitivedetectionofionsandbioimaging AT shulinong highlyluminescentnucleosidebasednpdopedcarbondotsforsensitivedetectionofionsandbioimaging AT wenzhusong highlyluminescentnucleosidebasednpdopedcarbondotsforsensitivedetectionofionsandbioimaging AT xianpengzhang highlyluminescentnucleosidebasednpdopedcarbondotsforsensitivedetectionofionsandbioimaging AT shuangshen highlyluminescentnucleosidebasednpdopedcarbondotsforsensitivedetectionofionsandbioimaging AT guohongjian highlyluminescentnucleosidebasednpdopedcarbondotsforsensitivedetectionofionsandbioimaging AT xiangyaochen highlyluminescentnucleosidebasednpdopedcarbondotsforsensitivedetectionofionsandbioimaging AT zhanchaoli highlyluminescentnucleosidebasednpdopedcarbondotsforsensitivedetectionofionsandbioimaging AT lixu highlyluminescentnucleosidebasednpdopedcarbondotsforsensitivedetectionofionsandbioimaging AT lixu highlyluminescentnucleosidebasednpdopedcarbondotsforsensitivedetectionofionsandbioimaging |