A Temporospatial Study of Sympathetic Skin Response and Electroencephalogram in Oral Mucosa Thermal Perception
ObjectiveTo investigate the temporospatial changes in sympathetic skin response (SSR) and electroencephalogram (EEG) under thermal stimuli and to draw a topographic map of SSR threshold temperature of the oral mucosa.Materials and MethodsA total of 40 healthy volunteers (24 men, 16 women, mean age o...
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| Format: | Article |
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Frontiers Media S.A.
2022-07-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2022.907658/full |
| _version_ | 1818163870025383936 |
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| author | Hao Zhang Shengjing Hu Zhangang Wang Xiang Li Suogang Wang Gang Chen |
| author_facet | Hao Zhang Shengjing Hu Zhangang Wang Xiang Li Suogang Wang Gang Chen |
| author_sort | Hao Zhang |
| collection | DOAJ |
| description | ObjectiveTo investigate the temporospatial changes in sympathetic skin response (SSR) and electroencephalogram (EEG) under thermal stimuli and to draw a topographic map of SSR threshold temperature of the oral mucosa.Materials and MethodsA total of 40 healthy volunteers (24 men, 16 women, mean age of 23 ± 3) were enrolled. Thermal stimuli were applied to the 35 partitions of oral mucosa starting from 36°C at the gradience of 1°C and the lowest temperature evoked SSR was defined as SSR threshold temperature. SSR and EEG signals at 45, 48, 51, and 54°C were then recorded synchronously.ResultsThe SSR threshold temperature increased from the anterior areas to the posterior areas. No significant difference between bilateral corresponding areas or between genders was observed. The SSR amplitude value increased from 45 to 54°C in the same area, while the highest value was recorded on the tip of the tongue and decreased backwardly from the anterior area. There were significant differences in latency of SSR between the tip of the tongue and the molar areas of the oral cavity (p < 0.05). Reduction in the alpha frequency band was observed after thermal stimuli, and there were statistical differences between baseline and thermal stimuli in all four degrees of temperatures (p < 0.05).ConclusionThe result of the experiment revealed that the autonomic and central nervous system (CNS) played important roles in thermal perception of oral mucosa and could be helpful for better understanding of pathological mechanism of burning mouth syndrome (BMS). |
| first_indexed | 2024-12-11T16:56:25Z |
| format | Article |
| id | doaj.art-f84b722183fe4e1e89e2e13d4085ca98 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-12-11T16:56:25Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-f84b722183fe4e1e89e2e13d4085ca982022-12-22T00:57:58ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2022-07-011610.3389/fnins.2022.907658907658A Temporospatial Study of Sympathetic Skin Response and Electroencephalogram in Oral Mucosa Thermal PerceptionHao Zhang0Shengjing Hu1Zhangang Wang2Xiang Li3Suogang Wang4Gang Chen5Department of Oral and Maxillofacial Surgery, School of Stomatology, Tianjin Medical University, Tianjin, ChinaSchool of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, ChinaChangzhou Hospital of Traditional Chinese Medicine, Changzhou, ChinaDepartment of Oral Surgery, School of Dentistry, University of Birmingham, Birmingham, United KingdomSchool of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, ChinaDepartment of Oral and Maxillofacial Surgery, School of Stomatology, Tianjin Medical University, Tianjin, ChinaObjectiveTo investigate the temporospatial changes in sympathetic skin response (SSR) and electroencephalogram (EEG) under thermal stimuli and to draw a topographic map of SSR threshold temperature of the oral mucosa.Materials and MethodsA total of 40 healthy volunteers (24 men, 16 women, mean age of 23 ± 3) were enrolled. Thermal stimuli were applied to the 35 partitions of oral mucosa starting from 36°C at the gradience of 1°C and the lowest temperature evoked SSR was defined as SSR threshold temperature. SSR and EEG signals at 45, 48, 51, and 54°C were then recorded synchronously.ResultsThe SSR threshold temperature increased from the anterior areas to the posterior areas. No significant difference between bilateral corresponding areas or between genders was observed. The SSR amplitude value increased from 45 to 54°C in the same area, while the highest value was recorded on the tip of the tongue and decreased backwardly from the anterior area. There were significant differences in latency of SSR between the tip of the tongue and the molar areas of the oral cavity (p < 0.05). Reduction in the alpha frequency band was observed after thermal stimuli, and there were statistical differences between baseline and thermal stimuli in all four degrees of temperatures (p < 0.05).ConclusionThe result of the experiment revealed that the autonomic and central nervous system (CNS) played important roles in thermal perception of oral mucosa and could be helpful for better understanding of pathological mechanism of burning mouth syndrome (BMS).https://www.frontiersin.org/articles/10.3389/fnins.2022.907658/fullsympathetic skin responseelectroencephalogramautonomic nervous systemoral mucosathermal perception |
| spellingShingle | Hao Zhang Shengjing Hu Zhangang Wang Xiang Li Suogang Wang Gang Chen A Temporospatial Study of Sympathetic Skin Response and Electroencephalogram in Oral Mucosa Thermal Perception Frontiers in Neuroscience sympathetic skin response electroencephalogram autonomic nervous system oral mucosa thermal perception |
| title | A Temporospatial Study of Sympathetic Skin Response and Electroencephalogram in Oral Mucosa Thermal Perception |
| title_full | A Temporospatial Study of Sympathetic Skin Response and Electroencephalogram in Oral Mucosa Thermal Perception |
| title_fullStr | A Temporospatial Study of Sympathetic Skin Response and Electroencephalogram in Oral Mucosa Thermal Perception |
| title_full_unstemmed | A Temporospatial Study of Sympathetic Skin Response and Electroencephalogram in Oral Mucosa Thermal Perception |
| title_short | A Temporospatial Study of Sympathetic Skin Response and Electroencephalogram in Oral Mucosa Thermal Perception |
| title_sort | temporospatial study of sympathetic skin response and electroencephalogram in oral mucosa thermal perception |
| topic | sympathetic skin response electroencephalogram autonomic nervous system oral mucosa thermal perception |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2022.907658/full |
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